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Open AccessPtf1a inactivation in adult pancreatic acinar cells causes apoptosis through activation of the endoplasmic reticulum stress pathway
Pancreas transcription factor 1 subunit alpha (PTF1A) is one of the key regulators in pancreatogenesis. In adults, it transcribes digestive enzymes, but its other functions remain largely unknown. Recent condi...
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Article
Open AccessDiabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice
Endocrine and exocrine pancreas tissues are both derived from the posterior foregut endoderm, however, the interdependence of these two cell types during their formation is not well understood. In this study, ...
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Article
Open AccessImpact of Sox9 Dosage and Hes1-mediated Notch Signaling in Controlling the Plasticity of Adult Pancreatic Duct Cells in Mice
In the adult pancreas, there has been a long-standing dispute as to whether stem/precursor populations that retain plasticity to differentiate into endocrine or acinar cell types exist in ducts. We previously ...
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Article
Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
Yoshiya Kawaguchi and colleagues show that a Sox9-positive progenitor pool located in the epithelia of the biliary and pancreatic ducts of adult mice serves as a continuous source of intestinal cells, hepatocy...
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Book
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Chapter
High-Voltage Tolerant Circuits
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Chapter
Variability Issue in the Nanometer Era
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Chapter
Ultra-Low Voltage Nano-Scale DRAM Cells
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Chapter
Leakage Reduction for Logic Circuits in RAMs
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Chapter
Reference Voltage Generators
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Chapter
Voltage Up-Converters and Negative Voltage Generators
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Chapter
An Introduction to LSI Design
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Chapter
Ultra-Low Voltage Nano-Scale SRAM Cells
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Chapter
Voltage Down-Converters
