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    Article

    Production and Evaluation of Ag85B:HspX:hFcγ1 Immunogenicity as an Fc Fusion Recombinant Multi-Stage Vaccine Candidate Against Mycobacterium tuberculosis

    An urgent need is to introduce an effective vaccine against Mycobacterium tuberculosis (M.tb) infection. In the present study, a multi-stage M.tb immunodominant Fcγ1 fusion protein (Ag85B:HspX:hFcγ1) was designed...

    Mohsen Karbalaei, Arman Mosavat, Saman Soleimanpour, Hadi Farsiani in Current Microbiology (2024)

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    Article

    Antimicrobial peptides: natural or synthetic defense peptides against HBV and HCV infections

    According to the literature, treatment of HCV and HBV infections faces challenges due to problems such as the emergence of drug-resistant mutants, the high cost of treatment, and the side effects of current an...

    Masoud Keikha, Hossein Kamali, Kiarash Ghazvini, Mohsen Karbalaei in VirusDisease (2022)

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    Article

    Evaluation of Mutations Related to Streptomycin Resistance in Mycobacterium tuberculosis Clinical Isolates

    Drug resistance to streptomycin in the clinical isolates of Mycobacterium tuberculosis (MTB) needs special consideration. It can mostly be caused by mutations in four genes with the names rpsL, rrs, gidB, and whi...

    Maryam Shafipour, Hesamaddin Shirzad-Aski, Abdolmajid Mohammadzadeh in Current Microbiology (2022)

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    Article

    Antimicrobial Peptides as a Promising Therapeutic Strategy for Neisseria Infections

    Antibiotic resistance is already widespread in the world, and it has become a great health problem. Therefore, comprehensive efforts are needed to minimize the resistance. The exploration of alternative therap...

    Parvin Askari, Masoud Yousefi, Mohsen Foadoddini, Alireza Neshani in Current Microbiology (2022)

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    Article

    Green synthesis of selenium nanoparticles using Rosmarinus officinalis and investigated their antimicrobial activity

    The interest of many has been attracted by plant-mediated synthesizing procedures for nanoparticles since they provide certain qualities including being cost-effective, quick, and compatible with the environme...

    Fatemeh Adibian, Roya Saddat Ghaderi, Zahra Sabouri, Javid Davoodi in BioMetals (2022)

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    Article

    Mycobacterium tuberculosis ty** using Allele-specific oligonucleotide multiplex PCR (ASO–PCR) method

    Mycobacterium tuberculosis (M. tuberculosis) genoty** provides valuable information related to the origin and the evolution of the isolates. This study aimed to evaluate the applicability of single-nucleotide p...

    Maryam Shafipour, Hesamaddin Shirzad-Aski, Ezzat Allah Ghaemi in Current Microbiology (2021)

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    Article

    Inconsistency of QuantiFERON-TB Gold Test and Tuberculin Skin Test Results in the Evaluation of Latent Tuberculosis Infection in Health Care Workers

    Problem considered: Working in hospital wards, especially the infectious and pulmonary diseases wards, increases the likelihood of the risk of the health care staff with a variety of infectious factors, including...

    Zahra Bagheri, Atieh Yaghoubi, Faezeh Sabet in Molecular Genetics, Microbiology and Virol… (2021)

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    Article

    APC targeting enhances immunogenicity of a novel multistage Fc-fusion tuberculosis vaccine in mice

    Numerous studies have demonstrated that targeting immunogens to FcγR on antigen-presenting cells (APCs) can selectively uptake and increase cellular immunity in vitro and in vivo. Therefore, the present study was...

    Saman Soleimanpour, Hadi Farsiani, Arman Mosavat in Applied Microbiology and Biotechnology (2015)

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    Article

    Sequence Analysis of lip R: A Good Method for Molecular Epidemiology of Clinical Isolates of Mycobacterium tuberculosis

    Advances in DNA sequencing have greatly enhanced the molecular epidemiology studies. In order to assess evolutionary and phylogenetic relation of Mycobacterium tuberculosis isolates several gene targets were eva...

    Samaneh Saedi, Masoud Youssefi, Hadi Safdari, Saman Soleimanpour in Current Microbiology (2015)