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Article
Long-term results of deep brain stimulation in a cohort of eight children with isolated dystonia
Pallidal deep brain stimulation (DBS) is an established treatment for patients with severe isolated dystonia. However, clinical evidence for the long-term use of DBS in children is limited and controlled trial...
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Chapter and Conference Paper
Cerebral Microdialysis in Acutely Brain-Injured Patients with Spreading Depolarizations
Multimodal cerebral monitoring was utilized to examine the relationship between pathological changes in microdialysis parameters and the occurrence of spreading depolarizations (SD) in brain-injured patients. ...
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Article
Transorbital penetrating head injury by a toilet brush handle
Transorbital penetrating brain injuries are rare lesions without defined therapy standards.
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Article
Intrakranielle Druck-Volumen-Beziehung
Die posttraumatische Hirndrucksteigerung hat einen signifikanten Einfluss auf die Prognose nach einem Schädel-Hirn-Trauma. Nach Ausschöpfung sämtlicher Kompensationsmöglichkeiten steigt der Hirndruck exponenti...
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Chapter and Conference Paper
Quantification of transient ischemic and metabolic events in patients after subarachnoid haemorrhage
Secondary insults after brain injury are preventable and/or treatable events affecting patients’ morbidity and mortality. Multimodal cerebral monitoring may allow one to detect such otherwise occult transient ...
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Chapter
Zerebrales Monitoring, neurophysiologisches Monitoring
Bei zerebral geschädigten Patienten besteht ein erhöhtes Risiko, aufgrund einer zerebralen Hypoxie bzw. Ischämie infolge arterieller Hypoxämie, arterieller Hypotonie oder intrakranieller Hypertension eine seku...
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Book
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Chapter and Conference Paper
Granulocyte colony-stimulating factor does not affect contusion size, brain edema or cerebrospinal fluid glutamate concentrations in rats following controlled cortical impact
Granulocyte colony-stimulating factor (G-CSF) is an established treatment in the neutropenic host. Usage in headinjured patients at risk for infection may aggravate brain damage. In contrast, evidence of G-CSF...
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Chapter and Conference Paper
Assessment of the relationship between age and continuous intracranial compliance
The aim of this open, descriptive and prospective study was to determine if the new monitoring parameter “continuous intracranial compliance (cICC)” decreases with age in patients with traumatic brain injury (...
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Chapter
Zerebrales Monitoring
Bei zerebral geschädigten Patienten besteht ein erhöhtes Risiko, aufgrund einer zerebralen Hypoxie bzw. Ischämie durch arterielle Hypoxämie, arterielle Hypotonie oder intrakranielle Hypertension eine sekundäre...
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Article
Multimodal Cerebral Monitoring in Comatose Head-Injured Patients
Monitoring of comatose patients in the neurosurgical intensive care unit (NICU) is constantly extended by the development of new methods for monitoring of cerebral function, metabolism and oxygenation. To sim...
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Chapter and Conference Paper
Cerebral Oxygenation in Contusioned vs. Nonlesioned Brain Tissue: Moniting of PtiO2 with Licox and Paratrend
Brain tissue PO2 in severely head injured patients was monitored in parallel with two different PO2-microsensors (Licox and Paratrend). Three different locations of sensor placement were chosen: (1) both catheter...
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Chapter and Conference Paper
Monitoring of Brain Tissue PO2 in Traumatic Brain Injury: Effect of Cerebral Hypoxia on Outcome
This study investigates the effect of hypoxic brain tissue PO2 on outcome, and examines the incidence of possible causes for cerebral hypoxia.
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Chapter and Conference Paper
Influence of Hyperventilation on Brain Tissue-PO2, PCO2, and pH in Patients with Intracranial Hypertension
A harmful effect of prolonged hyperventilation on outcome has been shown in comatose patients after severe head injury. The purpose of this study was to assess the acute effect of moderate hyperventilation for...
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Chapter and Conference Paper
Characterisation of Brain Edema Following “Controlled Cortical Impact Injury” in Rats
Significance, origin and nature of posttraumatic brain edema are still being debated. Recently, a “controlled cortical impact injury” (CCII) was introduced to model traumatic brain injury. Purpose of this stud...
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Chapter
Monitoring of Cerebral Oxygenation in Traumatic Brain Injured Patients
For many years, the sequel of traumatic brain injury distinguished between primary and secondary damage. Primary damage, caused by the physical forces associated with the trauma, occurs more or less instantly ...
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Chapter and Conference Paper
Mannitol Decreases ICP but Does Not Improve Brain-Tissue pO2 in Severely Head-Injured Patients with Intracranial Hypertension
Little is known about the effect of post-traumatic mannitol infusion on cerebral metabolism and oxygenation. The purpose of this study was to investigate the effects of mannitol in comatose patients on PtiO2, Pti...
