-
Article
Hibernoma-like brown fat in the bone marrow: report of a unique case
We report on a bone-marrow biopsy of a 61-year-old female patient that was performed because of the clinical suspicion of a myeloproliferative disease. The trephine biopsy showed morphological features that we...
-
Chapter and Conference Paper
Granulocyte colony-stimulating factor does not affect contusion size, brain edema or cerebrospinal fluid glutamate concentrations in rats following controlled cortical impact
Granulocyte colony-stimulating factor (G-CSF) is an established treatment in the neutropenic host. Usage in headinjured patients at risk for infection may aggravate brain damage. In contrast, evidence of G-CSF...
-
Article
Bulk glasses and ultrahard nanoceramics based on alumina and rare-earth oxides
Although often regarded as a network-former in conventional silicate glasses, Al2O3 alone cannot be obtained as a bulk glass. Until now, glasses comprising continuously linked [AlOx] polyhedra have been prepared ...
-
Article
Multifactorial resistance in patients with acute myeloid leukemia (AML): Coexpression of P-glycoprotein, the multidrug-resistance related protein (MRP) as well as heat shock proteins
-
Article
In patients with BCR-ABL-positive ALL in CR peripheral blood contains less residual disease than bone marrow: Implications for autologous BMT
Residual leukemic cells are detectable at frequencies as low as 1 in 106 normal cells in patients with Philadelphia chromosome/BCR-ABL-positive leukemias in complete remission (CR) using reverse-transcriptase pol...
-
Chapter and Conference Paper
Regulation of the Expression of ICAM-1 on Pre-B Cell Lines by TNF-α and IFN-γ
The intercellular adhesion molecule-1 (ICAM-1) belongs to the immunoglobulin supergene family and is found to be expressed on a variety of hematopoietic and non-hematopoietic cells [1]. ICAM-1 is a ljgand for ...
-
Article
Expression of insulin-like growth factor receptors I and II in normal human lung and in lung cancer
Insulin-like growth factors are potent mitogenic factors in human lung cancer in vitro, acting via specific receptors. Using monoclonal antibodies we demonstrate the expression of insulin-like growth factor re...
-
Article
Presence of more than two rearranged immunoglobulin heavy-chain genes in adult precursor B-cell acute lymphoblastic leukemia
We examined the configuration of the immunoglobulin genes in the leukemic blast cell DNA of 20 adults with precursor B-cell acute lymphoblastic leukemia (ALL), treated according to the BMFT protocol. Sixteen o...
-
Article
Abstract