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  1. No Access

    Article

    Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families

    The main genetic predisposition to type 1 diabetes (T1D) is known to be conferred by the HLA-DRB1, -DQA1 and -DQB1 genes in the major histocompatibility complex (MHC). Other genetic factors within this complex ar...

    M C Eike, M Olsson, D E Undlien, K Dahl-Jørgensen, G Joner… in Genes & Immunity (2009)

  2. Article

    Open Access

    Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes

    HLA, INS, PTPN22 and CTLA4 are considered to be confirmed type 1 diabetes susceptibility genes. HLA, PTPN22 and CTLA4 are known to be involved in immune regulation. Few studies have systematically investigated th...

    M. Bjørnvold, D. E. Undlien, G. Joner, K. Dahl-Jørgensen, P. R. Njølstad… in Diabetologia (2008)

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  3. Article

    The relation between size at birth and risk of type 1 diabetes is not influenced by adjustment for the insulin gene (-23HphI) polymorphism or HLA-DQ genotype

    Associations have been described between higher birthweight and increased risk of type 1 diabetes, and of insulin (INS) and human leucocyte antigen (HLA) genotypes that protect against diabetes with larger size a...

    L. C. Stene, P. M. Thorsby, J. P. Berg, K. S. Rønningen, D. E. Undlien… in Diabetologia (2006)

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  4. Article

    Erratum: Assessing the validity of the association between the SUMO4 M55V variant and risk of type 1 diabetes

    Nat. Genet. 37, 110–111 (2005). The authors' affiliations were mistakenly omitted. A complete list of authors and their affiliations follows. Deborah J Smyth1, Joanna M M Howson1, Christopher E Lowe1, Neil M W...

    D J Smyth, J M M Howson, C E Lowe, N M Walker, A C Lam, S Nutland… in Nature Genetics (2005)

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  5. Article

    40th EASD Annual Meeting of the European Association for the Study of Diabetes

    M. Veitenhansl, K. Stegner, F.-X. Hierl, C. Dieterle, H. Feldmeier, B. Gutt… in Diabetologia (2004)

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  6. No Access

    Article

    Testing the possible negative association of type 1 diabetes and atopic disease by analysis of the interleukin 4 receptor gene

    Variations in the interleukin 4 receptor A (IL4RA) gene have been reported to be associated with atopy, asthma, and allergy, which may occur less frequently in subjects with type 1 diabetes (T1D). Since atopy ...

    L M Maier, R C J Twells, J M M Howson, A C Lam, D G Clayton, D J Smyth… in Genes & Immunity (2003)

  7. Article

    Correlations between the incidence of childhood-onset Type I diabetes in Europe and HLA genotypes

    There are large variations in the incidence of Type I (insulin-dependent) diabetes mellitus within Europe, ranging from 3.2 cases per 100 000 person-years in the Republic of Macedonia to more than 40 new case...

    K. S. Rønningen, N. Keiding, A. Green in Diabetologia (2001)

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  8. No Access

    Article

    Susceptibility to human type 1 diabetes at IDDM2 is determined by tandem repeat variation at the insulin gene minisatellite locus

    The IDDM2 locus encoding susceptibility to type 1 diabetes was mapped previously to a 4.1–kb region spanning the insulin gene and a minisatellite or variable number of tandem repeats (VNTR) locus on human chromos...

    S.T. Bennett, A.M. Lucassen, S.C.L. Gough, E.E. Powell, D.E. Undlien… in Nature Genetics (1995)

  9. No Access

    Article

    Linkage disequilibrium map** of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31–q33

    The role of human chromosome 2 in type 1 diabetes was evaluated by analysing linkage and linkage disequilibrium at 21 microsatellite marker loci, using 348 affected sibpair families and 107 simplex families. T...

    J.B. Copeman, F. Cucca, C.M. Hearne, R.J. Cornall, P.W. Reed… in Nature Genetics (1995)

  10. Article

    IDDM susceptibility associated with polymorphisms in the insulin gene region A study of blacks, Caucasians and orientals

    Previous studies have suggested an association between polymorphisms in the insulin gene region and insulin-dependent diabetes mellitus (IDDM). Most of the studies so far have been performed in Caucasoid popul...

    Dr. D. E. Undlien, K. Hamaguchi, A. Kimura, E. Tuomilehto-Wolf… in Diabetologia (1994)

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  11. Article

    Particular HLA-DQ molecules play a dominant role in determining susceptibility or resistance to Type 1 (insulin-dependent) diabetes mellitus

    Genes in the HLA complex are by far the most important in determining genetic predisposition or resistance to Type 1 (insulin-dependent) diabetes mellitus. In this review evidence is presented that the HLA gen...

    E. Thorsby, K. S. RØnningen in Diabetologia (1993)

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  12. Article

    HLA antigens and cervical carcinoma

    Å. HELLAND, A. L. BØRRESEN, J. KAERN, K. S. RØNNINGEN, E. THORSBY in Nature (1992)

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