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Article
The associations between maternal pre-pregnancy body mass index or gestational weight change during pregnancy and body mass index of the child at 3 years of age
To estimate the associations between maternal pre-pregnancy body mass index (BMI) or gestational weight change (GWC) during pregnancy and offspring BMI at 3 years of age, while taking several pre-and postnatal...
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Article
A TLR2 polymorphism is associated with type 1 diabetes and allergic asthma
Type 1 diabetes (T1D) and allergic asthma are immune-mediated diseases. Pattern recognition receptors are proteins expressed by cells in the immune system to identify microbial pathogens and endogenous ligands...
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Article
Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families
The main genetic predisposition to type 1 diabetes (T1D) is known to be conferred by the HLA-DRB1, -DQA1 and -DQB1 genes in the major histocompatibility complex (MHC). Other genetic factors within this complex ar...
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Article
Open AccessJoint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes
HLA, INS, PTPN22 and CTLA4 are considered to be confirmed type 1 diabetes susceptibility genes. HLA, PTPN22 and CTLA4 are known to be involved in immune regulation. Few studies have systematically investigated th...
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Article
High prevalence of cardiovascular risk factors in children and adolescents with type 1 diabetes: a population-based study
The risk of dying of cardiovascular disease (CVD) before the age of 40 years is increased nearly 20-fold in patients with type 1 diabetes compared with non-diabetic persons. The aim of this study was to evalua...
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Article
The influence of dietary intake and meal pattern on blood glucose control in children and adolescents using intensive insulin treatment
We studied dietary factors and their association with blood glucose control in type 1 diabetic children and adolescents using intensive insulin treatment.
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Article
Children and adolescents with type 1 diabetes eat a more atherosclerosis-prone diet than healthy control subjects
We evaluated how well the diet of Norwegian children and adolescents with type 1 diabetes fulfils the Nordic and European dietary recommendations, focusing on parameters affecting prevention of atherosclerosis...
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Article
Atherosclerosis in childhood and adolescent type 1 diabetes: early disease, early treatment?
Autopsy studies have shown that atherosclerosis begins in adolescence in otherwise healthy individuals, and imaging techniques have shown that atherosclerosis develops earlier and is more prevalent in children...
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Article
The effect of 8 years of strict glycaemic control on peripheral nerve function in IDDM patients: the Oslo study
We have investigated the effect of long-term strict glycaemic control on peripheral and autonomic nerve function in 45 IDDM patients (age 18–42 years, diabetes duration 7–23 years) without clinical signs of ne...
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Article
Improvement of blood glucose control in IDDM patients retards the progression of morphological changes in early diabetic nephropathy
We investigated in a randomized, prospective study the influence of improved blood glucose control during 2-3 years in young insulin-dependent diabetic (IDDM) patients with microalbuminuria, which is indicativ...
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Article
Urinary albumin excretion rate and puberty in non-diabetic children and adolescents
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Article
Early glomerulopathy is present in young, Type 1 (insulin-dependent) diabetic patients with microalbuminuria
Increased urinary albumin excretion, microalbuminuria, may be the first sign of early diabetic nephropathy. We examined glomeruli by morphometric methods in 17 patients with Type 1 (insulin-dependent) diabetes...
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Article
Glomerular charge selectivity and the influence of improved blood glucose control in Type 1 (insulin-dependent) diabetic patients with microalbuminuria
We first compared glomerular charge selectivity index in two matched groups of Type 1 (insulin-dependent) diabetic patients with micro and normoalbuminuria respectively, and secondly, investigated prospectivel...
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Article
Diabetic control and microvascular complications: The near-normoglycaemic experience