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Article
Phosphatidylcholine hydroperoxide levels in human plasma are lower than previously reported
The quantification of PC hydroperoxide (PCOOH) in human plasma was studied by HPLC with chemiluminescence detection (HPLC-CL). We identified for the first time the monohydroperoxide of 1-palmitoyl-2-linoleoyl-...
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Article
Acute effect of ethanol on 7-hydroperoxycholesterol in muscle and liver
We tested the hypotheses that ethanol sensitivities of muscle and liver can be discerned in the initial periods of ethanol exposure, especially when acetaldehyde levels are markedly raised with cyanamide, an a...
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Article
Cholesterol-derived hydroperoxides in alcoholic liver disease
Human liver samples from 33 patients were collected at autopsy (controls’ n=9; fatty liver’ n=12; liver cirrhosis’ n=12)’ and samples homogenized. Lipids extracted with chloroform and methanol were injected into ...
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Article
Chemiluminescent determination of cholesterol hydroperoxides in human erythrocyte membrane
A method for separating, detecting, and quantifying cholesterol hydroperoxide (Ch-OOH) based on extraction, purification by solid-phase extraction cartridge, high-performance liquid chromatography with chemilu...
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Article
Epicoprostanol found in adipocere from five human autopsies
Adipocere formation is well known as a later postmortem change. We collected adipocere from five male victims which had been submerged under the sea or fresh water for 1 mon to 4 yr. Fresh subcutaneous fat of ...
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Article
Oxysterols found in opacified cornea of fish
We describe a new concept implicating oxidized cholesterol derivatives and very long-chain fatty acids as possible factors in the development of corneal opacification after death. Corneal tissues, removed from...