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    Article

    Rapid and sensitive quantification of paraquat and diquat in human serum by liquid chromatography/time-of-flight mass spectrometry using atmospheric pressure photoionization

    We developed a rapid and sensitive liquid chromatography/time-of-flight mass spectrometry (LC/TOF–MS) method using atmospheric pressure photoionization (APPI) for the determination of paraquat and diquat in hu...

    Naoki Yoshioka, Migiwa Asano, Azumi Kuse, Tomofumi Matsuoka in Forensic Toxicology (2012)

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    Article

    Phosphatidylcholine hydroperoxide levels in human plasma are lower than previously reported

    The quantification of PC hydroperoxide (PCOOH) in human plasma was studied by HPLC with chemiluminescence detection (HPLC-CL). We identified for the first time the monohydroperoxide of 1-palmitoyl-2-linoleoyl-...

    Junko Adachi, Naoki Yoshioka, Rika Funae, Yasushi Nagasaki, Takaeki Naito in Lipids (2004)

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    Consecutive administration of paraquat to rats induces enhanced cholesterol peroxidation and lung injury

    It is our hypothesis that as a consequence of increased oxidative stress, rats develop lung injury with increased cholesterol-derived hydroperoxides and oxysterols in lung after consecutive exposure of the rat...

    Junko Adachi, Kenji Ishii, Masafumi Tomita, Tetsuo Fujita in Archives of Toxicology (2003)