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    Chemiluminescent determination of cholesterol hydroperoxides in human erythrocyte membrane

    A method for separating, detecting, and quantifying cholesterol hydroperoxide (Ch-OOH) based on extraction, purification by solid-phase extraction cartridge, high-performance liquid chromatography with chemilu...

    Junko Adachi, Migiwa Asano, Takeaki Naito, Yasuhiro Ueno, Yoshitsugu Tatsuno in Lipids (1998)

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    Epicoprostanol found in adipocere from five human autopsies

    Adipocere formation is well known as a later postmortem change. We collected adipocere from five male victims which had been submerged under the sea or fresh water for 1 mon to 4 yr. Fresh subcutaneous fat of ...

    Junko Adachi, Yasuhiro Ueno, Atsuko Miwa, Migiwa Asano, Akiyoshi Nishimura in Lipids (1997)

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    Oxysterols found in opacified cornea of fish

    We describe a new concept implicating oxidized cholesterol derivatives and very long-chain fatty acids as possible factors in the development of corneal opacification after death. Corneal tissues, removed from...

    Junko Adachi, Keiko Hojo, Takeaki Naito, Yoshitsugu Tatsuno in Lipids (1996)

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    Identification of four metabolites of 3-(phenylamino)alanine, a constituent in l-tryptophan products implicated in eosinophiliamyalgia syndrome, in rats

    3-(Phenylamino)alanine (PAA), a contaminant found in l-tryptophan tablets, has been discussed as a possible cause of eosinophilia-myalgia syndrome (EMS). We administered PAA (100 mg/kg) by gastric gavage to Wista...

    Junko Adachi, Takaya Mio, Yasuhiro Ueno, Takeaki Naito in Archives of Toxicology (1994)

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    Article

    Accumulation of 1-methyl-tetrahydro-Β-carboline-3-carboxylic acid in blood and organs of rat. A possible causative substance of eosinophilia-myalgia syndrome associated with ingestion ofl-tryptophan

    1-Methyl-tetrahydro-Β-carboline-3-carboxylic acid (MTCA) may cause eosinophilia-myalgia syndrome (EMS) associated with ingestion ofl-tryptophan. The distribution and excretion of MTCA were studied in rats which h...

    Yumi Ogawa, Junko Adachi, Yoshitsugu Tatsuno in Archives of Toxicology (1993)

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    Metabolism and distribution in the rat of peak E substance, a constituent inl-tryptophan product implicated in eosinophilia-myalgia syndrome

    Peak E substance, 1,1′-ethylidenebis[tryptophan], a contaminant found inl-tryptophan tablets, has been suggested as a causative agent for eosinophilia-myalgia syndrome (EMS). Peak E substance (50 mg/kg) was admin...

    Junko Adachi, Takeaki Naito, Yasuhiro Ueno, Yumi Ogawa in Archives of Toxicology (1993)

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    Endogenous formation of 1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid in man as the possible causative substance of eosinophilia-myalgia syndrome associated with ingestion ofl-tryptophan

    1-Methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (MTCA) is now thought to be a possible causative substance of eosinophilia-myalgia syndrome associated with ingestion ofl-tryptophan. In the present study...

    Junko Adachi, Kenji Yamamoto, Yumi Ogawa, Yasuhiro Ueno in Archives of Toxicology (1991)