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Article
Environmentally Conscious In-Water Peptide Synthesis Using Boc Strategy
Seeking a more environmentally balanced method of peptide synthesis, we are focusing on develo** organic solvent-free synthetic methods using water, an environmentally friendly solvent. In current peptide sy...
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Article
Oligomerization of neutral peptides derived from the JC virus agnoprotein through a cysteine residue
The JC virus is the causative agent of progressive multifocal leukoencephalopathy. The viral genome encodes a multifunctional protein known as agnoprotein which is essential for viral proliferation and reporte...
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Article
Aqueous microwave-assisted solid-phase peptide synthesis using Fmoc strategy. III: Racemization studies and water-based synthesis of histidine-containing peptides
In this study, we describe the first aqueous microwave-assisted synthesis of histidine-containing peptides in high purity and with low racemization. We have previously shown the effectiveness of our synthesis ...
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Article
Open AccessDevelopment of a method for environmentally friendly chemical peptide synthesis in water using water-dispersible amino acid nanoparticles
Due to the vast importance of peptides in biological processes, there is an escalating need for synthetic peptides to be used in a wide variety of applications. However, the consumption of organic solvent is e...
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Article
Development of a Method for the Solid-Phase Peptide Synthesis in Water
Various organic solvents are routinely used in peptide synthesis, safe disposal of which are now an important environmental problem. To circumvent this problem, during the last few years we focused on developi...
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Chapter and Conference Paper
Synthesis of a RGD Peptide-PEG Hybrid for Carrying Adenovirus Vector into Cells
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Chapter and Conference Paper
Peptide Synthesis in Water: 2-(4-Sulfophenylsulfonyl)ethoxycarbonyl Group and Coupling Reagents
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Article
Oxysterols found in opacified cornea of fish
We describe a new concept implicating oxidized cholesterol derivatives and very long-chain fatty acids as possible factors in the development of corneal opacification after death. Corneal tissues, removed from...