5 Result(s)

Article

Selective FLT3 inhibition of FLT3-ITD⁺ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns

Acquired resistance to selective FLT3 inhibitors is an emerging clinical problem in the treatment of FLT3-ITD⁺ acute myeloid leukaemia (AML). The paucity of valid pre-clinical models has restricted investigations...

A S Moore, A Faisal, D Gonzalez de Castro, V Bavetsias, C Sun, B Atrash… in Leukemia (2012)

Article

Specific cytogenetic abnormalities are associated with a significantly inferior outcome in children and adolescents with mature B-cell non-Hodgkin's lymphoma: results of the FAB/LMB 96 international study

Clinical studies showed that advanced stage, high LDH, poor response to reduction therapy and combined bone marrow and central nervous system disease are significantly associated with a decreased event-free su...

H A Poirel, M S Cairo, N A Heerema, J Swansbury, A Aupérin, E Launay… in Leukemia (2009)

Article

Loci other than 21q22.12 (RUNX1) and 16q21–23.2 cause familial AML

G S Sellick, K Pritchard-Jones, V Shepherd, J Swansbury, D Catovsky… in Leukemia (2005)

Article

Secondary leukaemia characterised by monosomy 7 occurring post-autologous stem cell transplantation for AML

Secondary leukaemia has rarely been reported as a complication of autologous stem cell transplantation for AML. We report two cases of AML who presented with well-characterised cytogenetic abnormalities at pre...

KP Rege, SL Janes, R Saso, T Min, J Swansbury, RL Powles… in Bone Marrow Transplantation (1998)