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  1. Article

    Open Access

    Early circulating tumour DNA kinetics measured by ultra-deep next-generation sequencing during radical radiotherapy for non-small cell lung cancer: a feasibility study

    The evaluation of circulating tumour DNA (ctDNA) from clinical blood samples, liquid biopsy, offers several diagnostic advantages compared with traditional tissue biopsy, such as shorter processing time, reduc...

    G. M. Walls, L. McConnell, J. McAleese, P. Murray, T. B. Lynch… in Radiation Oncology (2020)

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  2. No Access

    Article

    Telomere length predicts progression and overall survival in chronic lymphocytic leukemia: data from the UK LRF CLL4 trial

    J C Strefford, L Kadalayil, J Forster, M J J Rose-Zerilli, A Parker, T T Lin… in Leukemia (2015)

  3. No Access

    Article

    Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns

    Acquired resistance to selective FLT3 inhibitors is an emerging clinical problem in the treatment of FLT3-ITD+ acute myeloid leukaemia (AML). The paucity of valid pre-clinical models has restricted investigations...

    A S Moore, A Faisal, D Gonzalez de Castro, V Bavetsias, C Sun, B Atrash… in Leukemia (2012)

  4. Article

    Open Access

    A comparison of three methods for detecting KRAS mutations in formalin-fixed colorectal cancer specimens

    KRAS mutation testing is required to select patients with metastatic colorectal cancer (CRC) to receive anti-epidermal growth factor receptor antibodies, but the optimal KRAS mutation test method is uncertain.

    D Gonzalez de Castro, B Angulo, B Gomez, D Mair, R Martinez… in British Journal of Cancer (2012)

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