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  1. No Access

    Reference Work Entry In depth

    Organic Matter BOD Biosensor Monitoring

    From a proposal of a microbial Biochemical Oxygen Demand (BOD) biosensor by Karube et al. in 1977, components (recognition elements, transducer, etc.) have so far been developed from various perspectives such ...

    Akihito Nakanishi, Wataru Yoshida, Isao Karube in Handbook of Cell Biosensors (2022)

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    Living Reference Work Entry In depth

    Organic Matter BOD Biosensor Monitoring

    From a proposal of a microbial Biochemical Oxygen Demand (BOD) biosensor by Karube et al. in 1977, components (recognition elements, transducer, etc.) have so far been developed from various perspectives such ...

    Akihito Nakanishi, Wataru Yoshida, Isao Karube in Handbook of Cell Biosensors

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    Chapter

    Yeast Based Sensors

    Since the first microbial cell sensor was studied by Karube et al. in 1977, many types of yeast based sensors have been developed as analytical tools. Yeasts are known as facultative anaerobes. Facultative ana...

    Mifumi Shimomura-Shimizu, Isao Karube in Whole Cell Sensing Systems I (2010)

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    Chapter

    Applications of Microbial Cell Sensors

    Since the first microbial cell sensor was studied by Karube et al. in 1977, many types of microbial cell sensors have been developed as analytical tools. The microbial cell sensor utilizes microbes as a sensin...

    Mifumi Shimomura-Shimizu, Isao Karube in Whole Cell Sensing System II (2010)

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    Chapter

    Development of Microbial Sensors and Their Application

    Many types of microbial sensors have been developed as analytical tools since the first microbial sensor was studied by Karube et al. in 1977. The microbial sensor consists of a transducer and microbe ...

    Hideaki Nakamura, Mifumi Shimomura-Shimizu, Isao Karube in Biosensing for the 21st Century (2008)

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    Article

    Current research activity in biosensors

    Biosensors consist of a molecular recognition element and a transducer. Since the first biosensor was developed by Updike and Hicks [1] many biosensors and their associated techniques have been studied and dev...

    Hideaki Nakamura, Isao Karube in Analytical and Bioanalytical Chemistry (2003)

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    Article

    Observation and Application of a Pattern in a DNA-Histone Mixture

    Satoshi Sasaki, Isao Karube in Analytical Sciences (2001)

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    Article

    Isolation of a bacterium from mangrove soil for degradation of sea sludge

    Sea sludge, which is sediment of fish excrement and sewage on the sea bottom, continues to be a serious environmental problem. It has the potential to cause eutrophication and red tide, resulting in the death ...

    Yoshihiro Ando, Naoya Mitsugi, Kazuyoshi Yano… in Applied Biochemistry and Biotechnology (2001)

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    Article

    Sensor Chip Using a Plasma-polymerized Film for Surface Plasmon Resonance Biosensors: Reliable Analysis of Binding Kinetics

    Hitoshi Muguruma, Ryohei Nagata, Runa Nakamura, Kimiharu Sato… in Analytical Sciences (2000)

  10. No Access

    Article

    Eicosapentaenoic acid release from the red alga Pachymeniopsis lanceolata by enzymatic degradation

    Forty-eight species of seaweeds from Japanese waters were screened for the valuable polyunsaturated fatty acids eicosapentaenoic acid (EPA). The eight species that contained the highest levels of these compoun...

    Ritsuko Matsukawa, Kiyotaka Hatakeda, Shota Ito… in Applied Biochemistry and Biotechnology (1999)

  11. No Access

    Article

    Purification of single stranded DNA from asymmetric PCR product using the SMART system

    A method has been developed using the SMART system for the purification of single stranded DNA from a mixture containing single- and double-stranded DNA amplified using asymmetric PCR. The asymmetric PCR produ...

    Eriko Kai, Koichi Sumikura, Kazunori Ikebukuro, Isao Karube in Biotechnology Techniques (1998)

  12. No Access

    Article

    Enzymatic screening of microalgae as a potential source of natural antioxidants

    Extracts of over 100 species of microalgae both from nature and from laboratory cultures were screened for antioxidant activity. As an assay for antioxidant function, we examined the inhibition of the activity...

    Ritsuko Matsukawa, Zvy Dubinsky, Kazuyoshi Masaki… in Applied Biochemistry and Biotechnology (1997)

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    Article

    Photo-induced activation of cytochrome P450/reductase fusion enzyme coupled with spinach chloroplasts

    Photoactivation of cytochrome P450 monooxygenase was studied using a combination of spinach chloroplasts and yeast microsomes containing rat P4501A1/yeast reductase fusion enzyme. Under illumination, in the re...

    Young-Sug Kim, Masayuki Hara, Kazunori Ikebukuro, Jun Miyake… in Biotechnology Techniques (1996)

  14. No Access

    Article

    Determination of cyanide using a microbial sensor

    A microbial cyanide sensor was prepared, consisting of immobilizedSaccharomyces cerevisiae and an oxygen electrode. When the electrode was inserted into a solution containing glucose, the respiration activity of ...

    Keijiro Nakanishi, Kazunori Ikebukuro… in Applied Biochemistry and Biotechnology (1996)

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    Article

    A novel synthesis method for cyclodextrins from maltose in water-organic solvent systems

    A novel enzymatic synthesis method of cyclodextrin (CD) from low-mol-wt maltose using cyclomaltodextrin glucanotransferase (CGTase) fromBacillus macerans has been developed in various water-organic solvent system...

    Takashi Morita, Nobuyuki Yoshida, Isao Karube in Applied Biochemistry and Biotechnology (1996)

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    Article

    Enzymatic hydrolysis of starch in water-immiscible organic solvent, two-phase systems

    Enzyme-catalyzed hydrolyzations of starch by α-amylase have been studied in various two-phase systems, consisting of water and a water-immiscible organic solvent. The hydrolytic conversion of soluble starch to...

    Takashi Morita, Isao Karube in Applied Biochemistry and Biotechnology (1995)

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    Article

    Influence of cationic antibiotics on phase behavior of rough-form lipopolysaccharide

    The rough-form lipopolysaccharide (LPS) interacted with cationic antibiotic polymyxin B and gramicidin S in solution, and showed altered thermotropic phase behavior and viscoelasticity. The phase behavior was ...

    Satoshi Fukuoka, Isao Karube in Applied Biochemistry and Biotechnology (1994)

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    Article

    Research and development of biosensors in Japan

    Isao Karube in Applied Biochemistry and Biotechnology (1993)

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    Chapter and Conference Paper

    Development of Micro—Biosensors for Brain Research

    Neurotransmitters play important roles in the brain since they are the key link in communication between neurons. Acetylcholine is the transmitter of motor neurons in the spinal cord as well as in all the nerv...

    Eiichi Tamiya, Isao Karube in Bioproducts and Bioprocesses 2 (1993)

  20. No Access

    Chapter

    Microbial Sensors and Microbiosensors

    A novel BOD sensor with a new principle employing a luminous bacterium, Photobacterium phosphoreum, was developed. The increased intensity of luminescence resulting from the cellular assimilation of organic compo...

    Isao Karube, Kenji Yokoyama in Uses of Immobilized Biological Compounds (1993)

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