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Strategic Action Line LI1: Personalised Production
The objective of this chapter is to describe the action line related to Personalised production (LI1). In particular, this chapter proposes research and innovation priorities aimed at promoting industrial syst...
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Article
Open AccessLumped-parameter model as a non-invasive tool to assess coronary blood flow in AAOCA patients
Anomalous aortic origin of the coronary artery (AAOCA) is a rare disease associated with sudden cardiac death, usually related to physical effort in young people. Clinical routine tests fail to assess the isch...
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Article
Special issue: Numerical simulation for additive manufacturing processes and products
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Article
Open AccessTwo-level method part-scale thermal analysis of laser powder bed fusion additive manufacturing
Numerical simulations of a complete laser powder bed fusion (LPBF) additive manufacturing (AM) process are extremely challenging, or even impossible, to achieve without a radical model reduction of the complex...
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Article
Open AccessA continuous model for the simulation of manufacturing swarm robotics
Manufacturing large and/or complex structural components is today non-trivial and far-too expensive, due to limitations in the state-of-the-art production processes. Swarm robotics could then bring a different...
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Article
Open AccessA coupled multiphase Lagrangian-Eulerian fluid-dynamics framework for numerical simulation of Laser Metal Deposition process
We present a Computational Fluid Dynamics (CFD) framework for the numerical simulation of the Laser Metal Deposition (LMD) process in 3D printing. Such a framework, comprehensive of both numerical formulations...
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Open AccessEarly-age creep behaviour of 3D printable mortars: Experimental characterisation and analytical modelling
The construction sector is experiencing significant technological innovations with digitalisation tools and automated construction techniques, such as additive manufacturing. Additive manufacturing utilising c...
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Article
Open AccessMixed variational formulations for structural topology optimization based on the phase-field approach
We propose a variational principle combining a phase-field functional for structural topology optimization with a mixed (three-field) Hu–Washizu functional, then including directly in the formulation equilibri...
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Article
Open AccessShape fidelity and sterility assessment of 3D printed polycaprolactone and hydroxyapatite scaffolds
Polycaprolactone (PCL) and hydroxyapatite (HA) composite are widely used in tissue engineering (TE). They are fit to being processed with three-dimensional (3D) printing technique to create scaffolds with veri...
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Article
Open AccessGeometric Analysis to Determine Kinking and Shortening of Bridging Stents After Branched Endovascular Aortic Repair
To evaluate bridging stent geometry in patients who underwent branched endovascular aortic repair (B-EVAR) and to correlate the outcomes with intrinsic bridging stent characteristics aiming to identify the ste...
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Article
Open AccessCorrection to: The androgen receptor/filamin A complex as a target in prostate cancer microenvironment
A Correction to this paper has been published: https://doi.org/10.1038/s41419-021-03483-4
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Open AccessThe androgen receptor/filamin A complex as a target in prostate cancer microenvironment
Prostate cancer represents the major cause of cancer-related death in men and patients frequently develop drug-resistance and metastatic disease. Most studies focus on hormone-resistance mechanisms related to ...
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Article
Open AccessNumerical Evaluation of Advanced Laser Control Strategies Influence on Residual Stresses for Laser Powder Bed Fusion Systems
Process-dependent residual stresses are one of the main burdens to a widespread adoption of laser powder bed fusion technology in industry. Residual stresses are directly influenced by process parameters, such...
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Article
Open AccessDiffusion–reaction compartmental models formulated in a continuum mechanics framework: application to COVID-19, mathematical analysis, and numerical study
The outbreak of COVID-19 in 2020 has led to a surge in interest in the research of the mathematical modeling of epidemics. Many of the introduced models are so-called compartmental models, in which the total quan...
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Article
Open Access3D Automatic Segmentation of Aortic Computed Tomography Angiography Combining Multi-View 2D Convolutional Neural Networks
The quantitative analysis of contrast-enhanced Computed Tomography Angiography (CTA) is essential to assess aortic anatomy, identify pathologies, and perform preoperative planning in vascular surgery. To overc...
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Article
Open AccessAndrogens Induce Invasiveness of Triple Negative Breast Cancer Cells Through AR/Src/PI3-K Complex Assembly
Breast cancer (BC) is still characterized by high morbidity and mortality. A specific BC subtype named triple negative BC (TNBC) lacks estrogen and progesterone receptors (ER and PR, respectively) and is chara...
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Hospital Factory for Manufacturing Customised, Patient-Specific 3D Anatomo-Functional Models and Prostheses
The fabrication of personalised prostheses tailored on each patient is one of the major needs and key issues for the future of several surgical specialties. Moreover, the production of patient-specific anatomo...
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Article
Erratum to: Computational Methods for Elastoplasticity: An Overview of Conventional and Less‑Conventional Approaches
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Article
Open AccessPlanar Timoshenko-like model for multilayer non-prismatic beams
This paper aims at proposing a Timoshenko-like model for planar multilayer (i.e., non-homogeneous) non-prismatic beams. The main peculiarity of multilayer non-prismatic beams is a non-trivial stress distributi...
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Open AccessCross-talk between androgen receptor and nerve growth factor receptor in prostate cancer cells: implications for a new therapeutic approach