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  1. No Access

    Article

    Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

    Chromatin is a dynamic macromolecular structure epigenetically modified to regulate specific gene expression. Altered chromatin function can lead to aberrant expression of growth regulators and may, ultimately...

    Angela Nebbioso, Nicole Clarke, Emilie Voltz, Emmanuelle Germain… in Nature Medicine (2005)

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    Article

    Inhibition of Human Breast Cancer Cell Growth by Blockade of the Mevalonate-Protein Prenylation Pathway is not Prevented by Overexpression of Cyclin D1

    Overexpression of the cyclin D1 (CCND1) gene, encoding a downstream effector of mitogenic signals that plays a central role in G1 phase progression, is often found in cancerous cells. In sporadic breast cancer (B...

    Domenico Germano, Carmen Pacilio, Massimo Cancemi… in Breast Cancer Research and Treatment (2001)

  3. Article

    Gene expression monitoring in hormone-responsive human breast cancer cells during estrogen-induced cell cycle progression

    Luigi Cicatiello, Angelo Facchiano, Raffaele Calogero… in Nature Genetics (2001)

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    Chapter and Conference Paper

    Transcriptional Control of Cell Cycle Progression by Estrogenic Hormones: Regulation of Human Cyclin D1 Gene Promoter Activity by Estrogen Receptor-a

    Estrogens (Es) are mitogens for breast and uterine epithelial cells, where they exert also a tumor-promoting action that appears to be directly linked to their growth promoting effects (1-3). Although during r...

    Valeria Belsito Petrizzi, Luigi Cicatiello, Lucia Altucci… in Hormonal Carcinogenesis III (2001)

  5. Article

    Sinking of ‘Cavtat’

    FRANCESCO BRESCIANI in Nature (1977)

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    Article

    Mechanism of X-ray Inhibition of the Sodium Pump in Human Erythrocytes: Adenotriphosphatase Activity of Stromata

    PREVIOUS results have shown that X-irradiation of human erythrocytes decreases the active efflux of sodium (sodium pump)1. However, 890 rads and 4,450 rads, which are effective in inducing a 45 and 73 per cent de...

    FRANCESCO BRESCIANI, FERDINANDO AURICCHIO, CESARE FIORE in Nature (1962)