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  1. Article

    Open Access

    Using the QI Maturity Tool – Modified Ontario Version to assess the state of QI maturity in Ontario’s public health units

    Implementation of quality improvement (QI) practices varies considerably among public health units (PHUs) in Ontario. With the emphasis on continuous quality improvement (CQI) in the revised Ontario Public Hea...

    Madelyn P. Law, Alex Berry, Nicole Clarke, Graham Hay… in Archives of Public Health (2021)

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  2. Article

    Open Access

    Targeting monoamine oxidase A-regulated tumor-associated macrophage polarization for cancer immunotherapy

    Targeting tumor-associated macrophages (TAMs) is a promising strategy to modify the immunosuppressive tumor microenvironment and improve cancer immunotherapy. Monoamine oxidase A (MAO-A) is an enzyme best know...

    Yu-Chen Wang, ** Wang, Jiaji Yu, Feiyang Ma, Zhe Li, Yang Zhou… in Nature Communications (2021)

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  3. No Access

    Article

    Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells

    Chromatin is a dynamic macromolecular structure epigenetically modified to regulate specific gene expression. Altered chromatin function can lead to aberrant expression of growth regulators and may, ultimately...

    Angela Nebbioso, Nicole Clarke, Emilie Voltz, Emmanuelle Germain… in Nature Medicine (2005)