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Article
Value of high spatial and high temporal resolution magnetic resonance angiography for differentiation between idiopathic and thromboembolic pulmonary hypertension: initial results
Differentiation between different forms of pulmonary hypertension (PH) is essential for correct disease management. The goal of this study was to elucidate the clinical impact of high spatial resolution MR ang...
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Article
Open AccessAcute effects of exercise on the inflammatory state in patients with idiopathic pulmonary arterial hypertension
Exercise training positively influences exercise tolerance and functional capacity of patients with idiopathic pulmonary arterial hypertension (IPAH). However, the underlying mechanisms are unclear. We hypothe...
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Article
Open AccessRiociguat in patients with chronic thromboembolic pulmonary hypertension: results from an early access study
Following positive results from the Phase III CHEST-1 study in patients with inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH), the Phase IIIb CTEPH early access study (E...
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Article
Combined automated 3D volumetry by pulmonary CT angiography and echocardiography for detection of pulmonary hypertension
To assess the diagnostic accuracy of automated 3D volumetry of central pulmonary arteries using computed tomography pulmonary angiography (CTPA) for suspected pulmonary hypertension alone and in combination wi...
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Article
Open AccessDiagnostic accuracy of automated 3D volumetry of cardiac chambers by CT pulmonary angiography for identification of pulmonary hypertension due to left heart disease
To assess diagnostic accuracy of automated 3D volumetry of cardiac chambers based on computed tomography pulmonary angiography (CTPA) for the differentiation of pulmonary hypertension due to left heart disease...
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Article
Open AccessOral Treprostinil is Associated with Improved Survival in FREEDOM-EV and its Open-Label Extension
In the event-driven FREEDOM-EV trial, oral treprostinil delayed clinical worsening in patients with pulmonary arterial hypertension (PAH). Open-label extension studies offer additional data about tolerability,...
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Article
Open AccessHereditäre pulmonal-arterielle Hypertonie
Die hereditäre pulmonal-arterielle Hypertonie (PAH) kann durch Mutation in mindestens 18 Genen ausgelöst werden. Das am häufigsten veränderte Gen ist das für den „bone morphogenetic protein receptor 2“ (BMPR2). A...