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    Article

    Value of high spatial and high temporal resolution magnetic resonance angiography for differentiation between idiopathic and thromboembolic pulmonary hypertension: initial results

    Differentiation between different forms of pulmonary hypertension (PH) is essential for correct disease management. The goal of this study was to elucidate the clinical impact of high spatial resolution MR ang...

    Sebastian Ley, Christian Fink, Julia Zaporozhan, Mathias M. Borst in European Radiology (2005)

  2. Article

    Open Access

    Acute effects of exercise on the inflammatory state in patients with idiopathic pulmonary arterial hypertension

    Exercise training positively influences exercise tolerance and functional capacity of patients with idiopathic pulmonary arterial hypertension (IPAH). However, the underlying mechanisms are unclear. We hypothe...

    Lars Harbaum, Emilia Renk, Sara Yousef, Antonia Glatzel in BMC Pulmonary Medicine (2016)

  3. Article

    Open Access

    Riociguat in patients with chronic thromboembolic pulmonary hypertension: results from an early access study

    Following positive results from the Phase III CHEST-1 study in patients with inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH), the Phase IIIb CTEPH early access study (E...

    Vallerie V. McLaughlin, Pavel Jansa, Jens E. Nielsen-Kudsk in BMC Pulmonary Medicine (2017)

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    Article

    Combined automated 3D volumetry by pulmonary CT angiography and echocardiography for detection of pulmonary hypertension

    To assess the diagnostic accuracy of automated 3D volumetry of central pulmonary arteries using computed tomography pulmonary angiography (CTPA) for suspected pulmonary hypertension alone and in combination wi...

    Claudius Melzig, Stefan Wörz, Benjamin Egenlauf, Sasan Partovi in European Radiology (2019)

  5. Article

    Open Access

    Diagnostic accuracy of automated 3D volumetry of cardiac chambers by CT pulmonary angiography for identification of pulmonary hypertension due to left heart disease

    To assess diagnostic accuracy of automated 3D volumetry of cardiac chambers based on computed tomography pulmonary angiography (CTPA) for the differentiation of pulmonary hypertension due to left heart disease...

    Claudius Melzig, Thuy Duong Do, Benjamin Egenlauf, Sasan Partovi in European Radiology (2022)

  6. Article

    Open Access

    Oral Treprostinil is Associated with Improved Survival in FREEDOM-EV and its Open-Label Extension

    In the event-driven FREEDOM-EV trial, oral treprostinil delayed clinical worsening in patients with pulmonary arterial hypertension (PAH). Open-label extension studies offer additional data about tolerability,...

    Ekkehard Grünig, Franck Rahaghi, Jean Elwing, Carmine Dario Vizza in Advances in Therapy (2024)

  7. Article

    Open Access

    Hereditäre pulmonal-arterielle Hypertonie

    Die hereditäre pulmonal-arterielle Hypertonie (PAH) kann durch Mutation in mindestens 18 Genen ausgelöst werden. Das am häufigsten veränderte Gen ist das für den „bone morphogenetic protein receptor 2“ (BMPR2). A...

    Prof. Dr. Christina A. Eichstaedt, Memoona Shaukat, Ekkehard Grünig in Die Innere Medizin (2024)