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Article
Open AccessCD229 CAR T cells eliminate multiple myeloma and tumor propagating cells without fratricide
Multiple myeloma (MM) is a plasma cell malignancy and most patients eventually succumb to the disease. Chimeric antigen receptor (CAR) T cells targeting B-Cell Maturation Antigen (BCMA) on MM cells have shown ...
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Article
In vivo vaccination effect in multiple myeloma patients treated with the monoclonal antibody isatuximab
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Article
Open AccessAcute effects of exercise on the inflammatory state in patients with idiopathic pulmonary arterial hypertension
Exercise training positively influences exercise tolerance and functional capacity of patients with idiopathic pulmonary arterial hypertension (IPAH). However, the underlying mechanisms are unclear. We hypothe...
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Article
Open AccessCancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma
Most patients with multiple myeloma (MM) will relapse after an initial response and eventually succumb to their disease. This is due to the persistence of chemotherapy-resistant tumor cells in the patients’ bo...
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Article
Functional autoantibodies against SSX-2 and NY-ESO-1 in multiple myeloma patients after allogeneic stem cell transplantation
Multiple myeloma (MM) is the malignancy with the most frequent expression of the highly immunogenic cancer–testis antigens (CTA), and we have performed the first analysis of longitudinal expression, immunologi...