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Article
Combined automated 3D volumetry by pulmonary CT angiography and echocardiography for detection of pulmonary hypertension
To assess the diagnostic accuracy of automated 3D volumetry of central pulmonary arteries using computed tomography pulmonary angiography (CTPA) for suspected pulmonary hypertension alone and in combination wi...
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Chapter and Conference Paper
Spline-Based Multimodal Image Registration of 3D PLI Data of the Human Brain
Registration of high-resolution 3D polarized light images (PLI) to reference blockface images is necessary for the analysis of brain fiber structures. We present an automatic approach for the registration of h...
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Article
Aortic morphometry at endograft position as assessed by 3D image analysis affects risk of type I endoleak formation after TEVAR
The purpose of this study was to identify morphologic factors affecting type I endoleak formation and bird-beak configuration after thoracic endovascular aortic repair (TEVAR).
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Chapter and Conference Paper
3D Model-Based Segmentation of 3D Biomedical Images
A central task in biomedical image analysis is the segmentation and quantification of 3D image structures. A large variety of segmentation approaches have been proposed including approaches based on different ...
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Chapter
Cell Segmentation and Cell Splitting Based on Gradient Flow Tracking in Microscopic Images
We introduce a new approach for segmentation and splitting of cells in different types of microscopy images. Our approach is based on gradient flow tracking followed by local adaptive thresholding to extract n...
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Chapter
Quantification of the Aortic Morphology in Follow-Up 3D-MRA Images of Children
The segmentation of the thoracic aorta and its main branches from medical image data is an important task in vascular image analysis. We introduce a new model-based approach for the segmentation of these vesse...
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Article
True four-dimensional analysis of thoracic aortic displacement and distension using model-based segmentation of computed tomography angiography
Previous analyses of aortic displacement and distension using computed tomography angiography (CTA) were performed on double-oblique multi-planar reformations and did not consider through-plane motion. The aim...
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Article
Spline-Based Hybrid Image Registration using Landmark and Intensity Information based on Matrix-Valued Non-radial Basis Functions
We introduce a new approach for spline-based elastic image registration using both point landmarks and intensity information. With this approach, both types of information as well as a regularization based on ...
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Chapter and Conference Paper
Segmentation of Heterochromatin Foci Using a 3D Spherical Harmonics Intensity Model
We introduce a 3D model-based approach for automatic segmentation of 3D fluorescent heterochromatin foci from 3D microscopy images. The approach employs a new 3D parametric intensity model based on a spherical...
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Chapter and Conference Paper
Globally Minimal Path Method Using Dynamic Speed Functions Based on Progressive Wave Propagation
In this paper, we propose a novel framework which extends the classical minimal path methods. Usually, minimal path methods can be interpreted as the simulation of the outward propagation of a wavefront emanat...
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Chapter and Conference Paper
Globally Optimal Curvature-Regularized Fast Marching for Vessel Segmentation
We introduce a novel fast marching approach with curvature regularization for vessel segmentation. Since most vessels have a smooth path, curvature can be used to distinguish desired vessels from short cuts, whic...
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Chapter
Combined Model-Based and Region-Adaptive 3D Segmentation and 3D Co-Localization Analysis of Heterochromatin Foci
The nuclear organization of euchromatin and heterochromatin is important for genome regulation and cell function. Therefore, the analysis of heterochromatin formation and maintenance is an important topic in b...
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Chapter and Conference Paper
Model-Based Segmentation and Motion Analysis of the Thoracic Aorta from 4D ECG-Gated CTA Images
Pathologies of the thoracic aorta can alter the shape and motion pattern of the aorta throughout the cardiac cycle. For diagnosis and therapy planning, determination of the aortic shape and motion is important...
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Chapter
Aortic Arch Quantification using Efficient Joint Segmentation and Registration
Accurate aortic arch quantification is important for diagnosis and treatment of cardiovascular diseases. We introduce a new approach for the quantification of the aortic arch morphology with improved computati...
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Chapter
Model-Based Quantification of Small Tubular Structures in 3D Vascular Images
We introduce a new 3D tubular intensity model in conjunction with a model fitting scheme for accurate segmentation and quantification of small tubular structures in 3D vascular images. The tubular model is for...
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Chapter and Conference Paper
Combined Model-Based Segmentation and Elastic Registration for Accurate Quantification of the Aortic Arch
Accurate quantification of the morphology of vessels is important for diagnosis and treatment of cardiovascular diseases. We introduce a new approach for the quantification of the aortic arch morphology that c...
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Chapter and Conference Paper
Landmark-Based 3D Elastic Registration of Pre- and Postoperative Liver CT Data
The qualitative and quantitative comparison of pre- and postoperative image data is an important possibility to validate computer assisted surgical procedures. Due to deformations after surgery a non-rigid reg...
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Chapter and Conference Paper
Hybrid Spline-Based Multimodal Registration Using Local Measures for Joint Entropy and Mutual Information
We introduce a new hybrid approach for spline-based elastic registration of multimodal medical images. The approach uses point landmarks as well as intensity information based on local analytic measures for jo...
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Chapter and Conference Paper
Hybrid Spline-Based Multimodal Registration Using a Local Measure for Mutual Information
We introduce a new hybrid approach for spline-based elastic registration of multimodal medical images. The approach uses point landmarks as well as intensity information based on local analytic measures for mu...
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Chapter and Conference Paper
Probabilistic Tracking and Model-Based Segmentation of 3D Tubular Structures
We introduce a new approach for tracking-based segmentation of 3D tubular structures. The approach is based on a novel combination of a 3D cylindrical intensity model and particle filter tracking. In compariso...
