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Chapter
Application of Gold Nanorods in Cardiovascular Science
Cardiovascular disease is a significant global Cardiovascular disease is a significant global health problem. Effectively treating it and exercise, but also demands the development of novel tools for rapid dia...
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Chapter
The Biomechanical Environment and Impact on Tissue Fibrosis
The implantation of materials into the body elicits a foreign body response (FBR) that includes formation of a fibrous capsule around the implanted material. The formation of the fibrous capsule has many simil...
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Chapter
Discoidin Domain Receptors in Cardiac Development
Heart development is a complex process, involving temporally and spatially restricted morphogenic events that ultimately give rise to a multichambered heart. Discoidin domain receptors (DDRs) 1 and 2 are recep...
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Protocol
High-Aspect-Ratio Gold Nanorods: Their Synthesis and Application to Image Cell-Induced Strain Fields in Collagen Films
Gold nanoparticles are receiving considerable attention due to their novel properties and the potential variety of their uses. Long gold nanorods with dimensions of approximately 20 × 400 nm exhibit strong lig...
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Article
Temporal alterations in cardiac fibroblast function following induction of pressure overload
Increases in cardiovascular load (pressure overload) are known to elicit ventricular remodeling including cardiomyocyte hypertrophy and interstitial fibrosis. While numerous studies have focused on the mechani...
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Article
Adaptive Changes in Cardiac Fibroblast Morphology and Collagen Organization as a Result of Mechanical Environment
There is a growing body of work in the literature that demonstrates the significant differences between 2D versus 3D environments in cell morphologies, spatial organization, cell–ECM interactions, and cell sig...
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Chapter
The Role of the Extracellular Matrix and Its Receptors in Modulating Cardiac Development
Fundamental to the differentiation and morphogenesis of any organ is the interaction between its component cells and the extracellular matrix (ECM). In the early 1980s, the concept of dynamic reciprocity was i...
