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Application of Gold Nanorods in Cardiovascular Science

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Anisotropic and Shape-Selective Nanomaterials

Part of the book series: Nanostructure Science and Technology ((NST))

Abstract

Cardiovascular disease is a significant global Cardiovascular disease is a significant global health problem. Effectively treating it and exercise, but also demands the development of novel tools for rapid diagnosis and new therapeutics for treatment. The field of nanomaterials is making significant contributions to multiple health care problems in the areas of disease detection, imaging and drug delivery. Gold nanoparticles are particularly promising due to their ease of synthesis, biocompatibility and unique optical properties. In particular, gold nanorods having received much attention for their potential in the diagnosis and treatment of cancer, are now being examined for other biomedical applications. This chapter highlights efforts using gold nanorods in cardiovascular research in such areas as detection of cardiovascular disease, understanding cardiac cell response to nanomaterials and the ability of gold nanorods to alter the mechanical properties of model tissue constructs and cardiac valves .

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Acknowledgements

The authors would like to thank the National Institutes of Health (HL097214) and the Mid-Atlantic Affiliate of the American Heart Association (13GRNT17070086) for funding.

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Authors and Affiliations

  1. Department of Cell Biology and Anatomy, University of South Carolina School of Medicine, 6439 Garners Ferry Rd, Columbia, SC, 29209, USA

    Jack G. Goldsmith & Edie C. Goldsmith

  2. Department of Bioengineering, Clemson University, Clemson, SC, 29643, USA

    Heather L’Ecuyer & Delphine Dean

Authors
  1. Jack G. Goldsmith
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  2. Heather L’Ecuyer
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  4. Edie C. Goldsmith
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Correspondence to Edie C. Goldsmith .

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Editors and Affiliations

  1. Savannah River National Laboratory , Aiken, South Carolina, USA

    Simona E. Hunyadi Murph

  2. Savannah River National Laboratory , Aiken, South Carolina, USA

    George K. Larsen

  3. Savannah River National Laboratory , Aiken, SC, South Carolina, USA

    Kaitlin J. Coopersmith

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Goldsmith, J.G., L’Ecuyer, H., Dean, D., Goldsmith, E.C. (2017). Application of Gold Nanorods in Cardiovascular Science. In: Hunyadi Murph, S., Larsen, G., Coopersmith, K. (eds) Anisotropic and Shape-Selective Nanomaterials. Nanostructure Science and Technology. Springer, Cham. https://doi.org/10.1007/978-3-319-59662-4_14

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