19 Result(s)

Article

RPL5 on 1p22.1 is recurrently deleted in multiple myeloma and its expression is linked to bortezomib response

Chromosomal region 1p22 is deleted in ⩾20% of multiple myeloma (MM) patients, suggesting the presence of an unidentified tumor suppressor. Using high-resolution genomic profiling, we delimit a 58 kb minimal de...

I J F Hofman, M van Duin, E De Bruyne, L Fancello, G Mulligan, E Geerdens… in Leukemia (2017)

Article

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

Galectin-1 (Gal-1) is involved in tumoral angiogenesis, hypoxia and metastases. Actually the Gal-1 expression profile in multiple myeloma (MM) patients and its pathophysiological role in MM-induced angiogenesi...

P Storti, V Marchica, I Airoldi, G Donofrio, E Fiorini, V Ferri, D Guasco… in Leukemia (2016)

Article

Clostridium difficile 027 increasing detection in a teaching hospital in Rome, Italy

G. B. Orsi, C. Conti, C. Mancini, A. Giordano in Infection (2014)

Article

Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction

Hypoxia-inducible transcription factor-1 (HIF-1α) is overexpressed in multiple myeloma (MM) cells within the hypoxic microenvironment. Herein, we explored the effect of persistent HIF-1α inhibition by a lentiv...

P Storti, M Bolzoni, G Donofrio, I Airoldi, D Guasco, D Toscani, E Martella… in Leukemia (2013)

Article

HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients

The deregulation of the homeobox genes as homeoboxB (HOXB)-7 has been previously associated to tumor progression and angiogenesis; here we investigated the potential role of HOXB7 in the pro-angiogenic properties...

P Storti, G Donofrio, S Colla, I Airoldi, M Bolzoni, L Agnelli, M Abeltino… in Leukemia (2011)

Article

Human myeloma cells express the bone regulating gene Runx2/Cbfa1 and produce osteopontin that is involved in angiogenesis in multiple myeloma patients

Osteopontin (OPN) is a multifunctional bone matrix glycoprotein that is involved in angiogenesis, cell survival and tumor progression. In this study we show that human myeloma cells directly produce OPN and ex...

S Colla, F Morandi, M Lazzaretti, R Rizzato, P Lunghi, S Bonomini, C Mancini… in Leukemia (2005)

Article

Natural Gas Hazard (CO2, ²²² Rn) within a Quiescent Volcanic Region and Its Relations with Tectonics: The Case of the Ciampino-Marino Area, Alban Hills Volcano, Italy

Groundwater surveys were performed by detailed(around 300 sites) grid-analysis of water temperature, pH, redox potential, electrical conductivity, ²²²Rn, alkalinity and by calculating the pCO₂, throughout the Cia...

L. Pizzino, G. Galli, C. Mancini, F. Quattrocchi, P. Scarlato in Natural Hazards (2002)

Article

Groundwater, Radon Continuous Monitoring System (α-scintillation Counting) for Natural Hazard Surveillance

—A “quasi continuous mode” monitoring system to measure the radon concentration within a natural environment (mainly groundwater), was designed, assembled and tested, under collaboration between DINCE and ING,...

G. Galli, C. Mancini, F. Quattrocchi in pure and applied geophysics (2000)

Article

Engineering the Design of Usable Hypermedia

This paper presents a systematic method for designing hypermedia that are easy to use for various types of users, along with its application to a specific case study. The design phase is supported by the use o...

F. Paterno, C. Mancini in Empirical Software Engineering (1999)

Article

Porphyria cutanea tarda and hepatitis G and C virus infection

C. Mancini, D. Griso, D. Rivanera, A. Macrì… in European Journal of Clinical Microbiology … (1998)

Article

Evaluation of indeterminate sera for hepatitis C virus by assays using synthetic peptides

The development of new immunodiagnostic systems to study antibodies anti-HCV based on the use of synthetic peptides are potentially very important in the evaluation of indeterminate samples. We have compared t...

D. Rivanera, G. Lorino, D. Lilli, G. Dicuonzo… in European Journal of Epidemiology (1994)

Article

Thermal behaviour of mixed Sn and Ge phosphates

Pure and mixed Ge and Sn hydrogenphosphates, prepared either by refluxing in 8M H₃PO₄ or by hydrothermal treatment at 180° or 300°C, have been characterized in terms of chemical composition and thermal behaviour ...

A. La Ginestra, P. Patrono, A. Frezza, C. Mancini… in Journal of Thermal Analysis (1993)

Article

Detection of antibodies to hepatits C virus in dialysis patients

Dialysis patients are at risk for infection by a variety of blood-borne agents trasmitted within dialysis units.

D. Rivanera, D. Lilli, G. Lorino, V. Pirozzi… in European Journal of Epidemiology (1993)

Chapter

Welcome Address

On behalf of ENEA, the Italian State Commission for Research and Development of Nuclear and Alternative Energy Sources, which has organized this Seminar together with the Commission of the European Communities...

C. Mancini in New Separation Chemistry Techniques for Ra… (1991)

Chapter

Immunoregulation of “In Vitro” Antibody Response to Azobenzenearsonate (ABA)-Proteins

The impact of exogenous antigen on the immune system activates a complex series of events which determine the onset, intensity, and duration of the antibody response. This antigen-induced perturbation of the i...

G. Doria, C. Mancini, Giovanna Agarossi, Daniela Fioravanti, S. Vietri… in Immunoregulation (1983)

Article

Comparison between the minimum detection limits of radioisotope X-ray fluorescence technique and activation analysiś with a low intensity²⁵²Cf neutron source

A comparative study of radioactive X-ray fluorescence and neutron activation analysis using a low-intensity²⁵²Cf source has been carried out. X-ray fluorescence proved to be superior to NAA if ion-exchange precon...

R. Cesareo, C. Mancini in Journal of Radioanalytical Chemistry (1976)