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Article
Open AccessExpression of p89c-Mybex9b, an alternatively spliced form of c-Myb, is required for proliferation and survival of p210BCR/ABL-expressing cells
The c-Myb gene encodes the p75c-Myb isoform and less-abundant proteins generated by alternatively spliced transcripts. Among these, the best known is p89c-Mybex9b, which contains 121 additional amino acids betwee...
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Article
Silencing of endogenous IGFBP-5 by micro RNA interference affects proliferation, apoptosis and differentiation of neuroblastoma cells
Signal transduction through the IGF axis is implicated in proliferation, differentiation and survival during development and adult life. The IGF axis includes the IGF binding proteins (IGFBPs) that bind IGFs w...
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Article
Cyclin D1-dependent regulation of B-myb activity in early stages of neuroblastoma differentiation
Levels of the transcription factor B-myb must be down-regulated to allow terminal differentiation of neuroectodermal cells and yet its constitutive expression induces early markers of neural differentiation. T...
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Article
Neuroblastoma specific effects of DR-nm23 and its mutant forms on differentiation and apoptosis
DR-nm23 belongs to a gene family which includes nm23-H1, originally identified as a candidate metastasis suppressor gene. Nm23 genes are expressed in different tumor types where their levels have been alternat...
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Article
Thermophysical properties of polymers in aqueous two-phase systems
This work concentrated on very precise density measurements of aqueous twophase systems (ATPS). The relations between density and polymer concentration of solutions of binary systems were determined experiment...
