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    Article

    RPL5 on 1p22.1 is recurrently deleted in multiple myeloma and its expression is linked to bortezomib response

    Chromosomal region 1p22 is deleted in ⩾20% of multiple myeloma (MM) patients, suggesting the presence of an unidentified tumor suppressor. Using high-resolution genomic profiling, we delimit a 58 kb minimal de...

    I J F Hofman, M van Duin, E De Bruyne, L Fancello, G Mulligan, E Geerdens in Leukemia (2017)

  2. Article

    Erratum: A gene expression signature for high-risk multiple myeloma

    Correction to: Leukemia (2012) 26, 2406–2413; doi:10.1038/leu.2012.127 Since the publication of this article, the authors have discovered an error in the script for calculating the IFM-15 risk scores. In their...

    R Kuiper, A Broyl, Y de Knegt, M H van Vliet, E H van Beers, B van der Holt in Leukemia (2014)

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    Article

    A gene expression signature for high-risk multiple myeloma

    There is a strong need to better predict the survival of patients with newly diagnosed multiple myeloma (MM). As gene expression profiles (GEPs) reflect the biology of MM in individual patients, we built a pro...

    R Kuiper, A Broyl, Y de Knegt, M H van Vliet, E H van Beers, B van der Holt in Leukemia (2012)

  4. No Access

    Article

    Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma

    Events mediating transformation from the pre-malignant monoclonal gammopathy of undetermined significance (MGUS) to multiple myeloma (MM) are unknown. We analyzed gene expression data sets generated on the Aff...

    W-J Chng, G F Huang, T H Chung, S B Ng, N Gonzalez-Paz, T Troska-Price in Leukemia (2011)