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Article
Is Hyperbilirubinaemia a Clinical Useful Indicator of Reduced Drug Clearance Capacity in Neonates?
Background: There is extensive variability in clearance between neonates, mainly explained by age or size. We aimed to assess if hyperbilirubinaemia also contributes as covariate, using reported paracetamol [1] a...
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Article
Propofol pharmacokinetics in preterm and term neonates: the relevance of both postmenstrual and postnatal age
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Article
Pain in intensive care after sternotomy is predictive for chronic thoracic pain
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Chapter and Conference Paper
Self-adaptation of Genome Size in Artificial Organisms
In this paper we investigate the evolutionary pressures influencing genome size in artificial organisms. These were designed with three organisation levels (genome, proteome, phenotype) and are submitted to lo...