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Article
Open AccessRelationship Between Early Functional and Structural Brain Developments and Brain Injury in Preterm Infants
Recent studies explored the relationship between early brain function and brain morphology, based on the hypothesis that increased brain activity can positively affect structural brain development and that exc...
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Article
The role of near-infrared spectroscopy monitoring in preterm infants
Neurological morbidities such as peri/intraventricular hemorrhage and periventricular leukomalacia largely determine the neurodevelopmental outcome of vulnerable preterm infants and our aim should be to minimi...
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Article
Cefazolin plasma protein binding and its covariates in neonates
Cefazolin (CFZ) is highly and saturably bound to human serum albumin (HSA) in adults. We aim to describe CFZ protein binding and its covariates in neonates. In neonates to whom intravenous CFZ (50 mg/kg) was a...
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Article
473 Prospective Evaluation of Propylene Glycol Tolerance in (PRE) Term Neonates: An Active Comparator Approach
Introduction: Propylene glycol (PG) is a commonly used excipiens although accumulation can result in hyperosmolarity, renal toxicity and lactic acidosis. This is of concern in neonates given their limited meta...
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Article
1363 Empirical Mode Decomposition to Assess Coupling Between Infants Cry Signals and Pain Expression Quantified by a Pain Score
Introduction: Coupling between fundamental frequency variation and intensity contour during crying reflects the degree of maturation of the central nervous system. We recently described the use of Empirical Mo...
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Article
478 Haemodynamics Following Intravenous Paracetamol Administration in (PRE) Term Neonates
Introduction: There are recent observations on the haemodynamics of intravenous paracetamol (hypotension) in adult IC setting (1). We therefore evaluated the haemodynamics following iv paracetamol loading dose (2...
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Article
569 Single Center Long Term Follow-Up of Supratentorial Arachnoid Cysts in Children
Background and aims: Data on long-term follow-up of supratentorial arachnoid cysts in patients treated conservatively are limited. The perspective of this study was to evaluate the age at diagnosis (prenatally...
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Chapter and Conference Paper
Optimization of the Coherence Measurement Computed by Means of the Welch Averaged Periodogram Method for Assessment of Impaired Cerebral Autoregulation
The coherence method (COH) has been widely used to study the concordance between continuously measured signals intervening in the assessment of cerebral autoregulation in neonates. Several research groups have...
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Chapter and Conference Paper
The Partial Coherence Method for Assessment of Impaired Cerebral Autoregulation using Near-infrared Spectroscopy: Potential and Limitations
The most important forms of brain injury in premature infants are partly caused by disturbances in cerebral autoregulation. As changes in cerebral intravascular oxygenation (HbD), regional cerebral oxygen satu...
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Article
Propofol pharmacokinetics in preterm and term neonates: the relevance of both postmenstrual and postnatal age
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Article
Single-centre audit on the use of intravenous paracetamol in neonates
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Article
Use of the Liver Tissue Oxygenation Index as a Noninvasive Parameter of Intestinal Ischemia in Rabbits
The tissue oxygenation index (TOI), measured by spatially resolved spectroscopy (SRS), reflects the ratio between oxygenated and deoxygenated tissue hemoglobin. We investigated whether liver TOI is a noninvasi...
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Article
Pharmacokinetics of single intravenous bolus administration of propofol in preterm and term neonates
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Article
6 Impact of Administration of Analgesics During Neonatal Stay on Pain Expression Following Neonatal Stay in Former Preterm Infants
Introduction: There are still few data on the impact of pharmacologic treatment of pain during neonatal stay in preterm infants on pain expression after neonatal stay. We therefore investigated pain expression in...
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Article
Continuous infusion of medications in very low birth weight infants
To develop a safe and accurate method for the administration in the neonatal intensive care unit of several potent medications as a continuous infusion without overloading the infant, especially the very low b...
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Article
Prostaglandines en de neonatale nier: klinische relevantie van een fysiologisch evenwicht
The recognition of rare, iatrogenic complications is easier when the underlying physiology and pathophysiology is understood. This is illustrated by three observations in neonates in whom imbalance in prostagl...
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Article
Peroperatief beleid en langetermijnresultaten na cryotherapie
Retinopathy of prematurity still remains an important morbidity characteristic after preterm birth. Nowadays especially elbw-infants are at increased risk. We describe preoperative management and long-term ophtha...
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Article
About the rationale of the insertion of a Heimlich valve in the thoracostomy circuit in newborn infants and small children
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Article
Bradycardias on Home Monitoring As A First Sign of Intracranial Hypertension
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Article
Apneas on Polysomnography As A First Sign for Rsv-Bronchiolitis
