20 Result(s)
within
Anne C. Stone
English
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Article
Open AccessThe gut microbiome of exudivorous marmosets in the wild and captivity
Mammalian captive dietary specialists like folivores are prone to gastrointestinal distress and primate dietary specialists suffer the greatest gut microbiome diversity losses in captivity compared to the wild...
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Open AccessGeographically dispersed zoonotic tuberculosis in pre-contact South American human populations
Previous ancient DNA research has shown that Mycobacterium pinnipedii, which today causes tuberculosis (TB) primarily in pinnipeds, infected human populations living in the coastal areas of Peru prior to European...
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Open AccessGenomic skimming and nanopore sequencing uncover cryptic hybridization in one of world’s most threatened primates
The Brazilian buffy-tufted-ear marmoset (Callithrix aurita), one of the world’s most endangered primates, is threatened by anthropogenic hybridization with exotic, invasive marmoset species. As there are few gene...
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Open AccessMitogenomic phylogeny of Callithrix with special focus on human transferred taxa
Callithrix marmosets are a relatively young primate radiation, whose phylogeny is not yet fully resolved. These primates are naturally para- and allopatric, but three species with highly invasive potential have b...
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Dire wolves were the last of an ancient New World canid lineage
Dire wolves are considered to be one of the most common and widespread large carnivores in Pleistocene America1, yet relatively little is known about their evolution or extinction. Here, to reconstruct the evolut...
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Ancient DNA analysis
Although the first ancient DNA molecules were extracted more than three decades ago, the first ancient nuclear genomes could only be characterized after high-throughput sequencing was invented. Genome-scale da...
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The population genomics of within-host Mycobacterium tuberculosis
Recent progress in genomic sequencing from patient samples has allowed for the first detailed insight into the within-host genetic diversity of Mycobacterium tuberculosis (M.TB), revealing remarkably low levels o...
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Open AccessDifferential DNA methylation of vocal and facial anatomy genes in modern humans
Changes in potential regulatory elements are thought to be key drivers of phenotypic divergence. However, identifying changes to regulatory elements that underlie human-specific traits has proven very challeng...
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Getting sick in the Neolithic
Ancient Salmonella enterica genomes from humans beginning to adopt farming lifestyles reveal insight into how epidemiological pathways were affected by human cultural transitions.
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Open AccessMetagenomic analysis of dental calculus in ancient Egyptian baboons
Dental calculus, or mineralized plaque, represents a record of ancient biomolecules and food residues. Recently, ancient metagenomics made it possible to unlock the wealth of microbial and dietary information ...
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Open AccessOral microbiome diversity in chimpanzees from Gombe National Park
Historic calcified dental plaque (dental calculus) can provide a unique perspective into the health status of past human populations but currently no studies have focused on the oral microbial ecosystem of oth...
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Novel anelloviruses identified in buccal swabs of Antarctic fur seals
Viral diversity associated with Antarctic wildlife remains poorly studied. Nonetheless, over the past 5 years, there has been a concerted effort using viral metagenomics approaches to identify and characterize...
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Open AccessIn-solution Y-chromosome capture-enrichment on ancient DNA libraries
As most ancient biological samples have low levels of endogenous DNA, it is advantageous to enrich for specific genomic regions prior to sequencing. One approach—in-solution capture-enrichment—retrieves sequen...
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Open AccessDifferential preservation of endogenous human and microbial DNA in dental calculus and dentin
Dental calculus (calcified dental plaque) is prevalent in archaeological skeletal collections and is a rich source of oral microbiome and host-derived ancient biomolecules. Recently, it has been proposed that ...
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Open AccessA composite genome approach to identify phylogenetically informative data from next-generation sequencing
Improvements in sequencing technology now allow easy acquisition of large datasets; however, analyzing these data for phylogenetics can be challenging. We have developed a novel method to rapidly obtain homolo...
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Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis
Three 1,000-year-old mycobacterial genomes from Peruvian human skeletons reveal that a member of the Mycobacterium tuberculosis complex derived from seals caused human disease before contact in the Americas.
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Open AccessRapid evolution of BRCA1 and BRCA2in humans and other primates
The maintenance of chromosomal integrity is an essential task of every living organism and cellular repair mechanisms exist to guard against insults to DNA. Given the importance of this process, it is expected...
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Diet and the evolution of human amylase gene copy number variation
Starch consumption is a prominent characteristic of agricultural societies and hunter-gatherers in arid environments. In contrast, rainforest and circum-arctic hunter-gatherers and some pastoralists consume mu...
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Independent evolution of bitter-taste sensitivity in humans and chimpanzees
The ability to sense bitter taste is vital for detecting toxins in food. Phenylthiocarbamide (PTC) is unusual in that to us it tastes either very bitter, or almost tasteless, depending on an individual's genet...
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Ancient DNA gives green light to Galápagos Land Iguana repatriation
Land Iguanas, Conolophus subcristatus,were extirpated from Isla Baltra, GalápagosArchipelago in the 1940s. Historical recordsindicate that some Baltra iguanas weretranslocated to nearby Isla Seymour Norte inthe 1...
