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Article
Inferring the distribution of fitness effects in patient-sampled and experimental virus populations: two case studies
We here propose an analysis pipeline for inferring the distribution of fitness effects (DFE) from either patient-sampled or experimentally-evolved viral populations, that explicitly accounts for non-Wright-Fis...
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Article
Ethics of DNA research on human remains: five globally applicable guidelines
We are a group of archaeologists, anthropologists, curators and geneticists representing diverse global communities and 31 countries. All of us met in a virtual workshop dedicated to ethics in ancient DNA rese...
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Article
The population genomics of within-host Mycobacterium tuberculosis
Recent progress in genomic sequencing from patient samples has allowed for the first detailed insight into the within-host genetic diversity of Mycobacterium tuberculosis (M.TB), revealing remarkably low levels o...
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Article
Ancient mitochondrial DNA and population dynamics in postclassic Central Mexico: Tlatelolco (ad 1325–1520) and Cholula (ad 900–1350)
The past composition and genetic diversity of populations from Central Mexico during the Postclassic period (ad 900–1520) are still little understood. Two of the largest centres of ancient groups, Tlatelolco and ...
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Article
Open AccessSuccessful reconstruction of whole mitochondrial genomes from ancient Central America and Mexico
The northern and southern peripheries of ancient Mesoamerica are poorly understood. There has been speculation over whether borderland cultures such as Greater Nicoya and Casas Grandes represent Mesoamerican o...