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Article
Open AccessHigh serum alpha-fetoprotein and positive immunohistochemistry of alpha-fetoprotein are related to poor prognosis of gastric cancer with liver metastasis
Liver metastasis in gastric cancer is incurable. Alpha-fetoprotein-producing gastric cancer has a poor prognosis and is prone to liver metastasis. We investigated the association between preoperative serum alp...
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Article
Endoscopic mucosal ischemic index for predicting anastomotic complications after esophagectomy: a prospective cohort study
Postoperative complications related to gastric conduit reconstruction are still common issues after McKeown esophagectomy. A novel endoscopic mucosal ischemic index is desired to predict anastomotic complicati...
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Article
Prognostic significance of NY-ESO-1 antigen and PIGR expression in esophageal tumors of CHP-NY-ESO-1-vaccinated patients as adjuvant therapy
The aim of this study was to determine the efficacy and the biomarkers of the CHP-NY-ESO-1 vaccine complexed with full-length NY-ESO-1 protein and a cholesteryl pullulan (CHP) in patients with esophageal squam...
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Article
Immunotherapeutic advances in gastric cancer
Advanced gastric cancers are responsible for overwhelming human suffering and death. Despite the development of combination chemotherapies, the survival rates of patients with gastric cancer remain unsatisfact...
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Article
Downstaging and Histological Effects Might Be Reliable Predictors of the Efficacy of DOC+CDDP+5-FU (DCF) as Neoadjuvant Therapy for Stage III or Borderline Resectable Esophageal Cancer: a Single Institute Experience
In Japan, two courses of CDDP+5-FU (CF) therapy followed by surgery are accepted as a standard treatment for stage II/III esophageal cancer (EC) based on the results of the JCOG9907 trial. To gain a better sur...
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Article
Thoracoscopy–thoracotomy approach for an aortoesophageal fistula: a case report
An aortoesophageal fistula is often fatal, and standard radical surgery is highly invasive because both bilateral thoracotomy and laparotomy are required. We successfully incorporated thoracoscopic esophagecto...
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Article
Open AccessFormation of bridgmanite-enriched layer at the top lower-mantle during magma ocean solidification
Thermochemical heterogeneities detected today in the Earth’s mantle could arise from ongoing partial melting in different mantle regions. A major open question, however, is the level of chemical stratification...
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Article
Determination of elastic constants of single-crystal chromian spinel by resonant ultrasound spectroscopy and implications for fluid inclusion geobarometry
We determined elastic constants of a single-crystal chromian spinel at temperatures from −15 to 45 °C through the Rectangular Parallelepiped Resonance method. The sample is a natural chromian spinel, which was...
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Article
Open AccessEffect of cation substitution on bridgmanite elasticity: A key to interpret seismic anomalies in the lower mantle
Seismological observations show that, in some regions of the lower mantle, an increase in bulk sound velocity, interestingly, occurs in the same volume where there is a decrease in shear velocity. We show that...
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Article
Open AccessElastic anisotropy of experimental analogues of perovskite and post-perovskite help to interpret D′′ diversity
Recent studies show that the D′′ layer, just above the Earth's core–mantle boundary, is composed of MgSiO3 post-perovskite and has significant lateral inhomogeneity. Here we consider the D′′ diversity as related ...
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Article
Open AccessAnharmonic effect on the equation of state (EoS) for NaCl
We find clear intrinsic anharmonicity in the NaCl-B1 phase by examining the equation of state (EoS) based on previous ultrasonic velocity data for pressures up to 0.8 GPa and temperatures up to 800 K. The expe...
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Article
Ultrasonic measurements of single-crystal gold under hydrostatic pressures up to 8 GPa in a Kawai-type multi-anvil apparatus
Ultrasonic measurements were conducted on single-crystal gold at ambient condition and hydrostatic pressures up to 8 GPa at room temperature in a Kawai-type multi-anvil apparatus. The P-wave velocities measure...
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Article
Status of heavy element research using a gas-filled recoil separator at RIKEN
A gas-filled type of recoil separator for heavy element research was installed at an experimental hall of RIKEN Linear Accelerator facility to realize getting higher intensity of primary beam and long beam tim...
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Article
Intrinsic eigenvibration frequency in the resonant ultrasound spectroscopy: Evidence for a coupling vibration between a sample and transducers
The resonant ultrasound spectroscopy enables us to measure elastic constants of various materials with high accuracy. One of its curious features is resonance frequency shift caused by modulation of clamp forc...
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Chapter
The Use of Sintered Diamond Anvils in the MA8 Type High-pressure Apparatus
A new multi-anvil type high-presure apparatus has been developed using sintered diamond anvils to generate pressures over 30 GPa and temperatures up to about 2000°C. A maximum sample volume of about 1 mm3 is avai...
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Chapter
Performance of the Complete Travel-time Equation of State at Simultaneous High Pressure and Temperature
The complete travel-time equation of state (CT-EOS) is presented by utilizing thermodynamics relations, such as; <m:math display='blo...
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Article
The use of sintered diamond anvils in the MA8 type high-pressure apparatus
A new multi-anvil type high-presure apparatus has been developed using sintered diamond anvils to generate pressures over 30 GPa and temperatures up to about 2000°C. A maximum sample volume of about 1 mm3 is avai...
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Article
Performance of the complete travel-time equation of state at simultaneous high pressure and temperature
The complete travel-time equation of state (CT-EOS) is presented by utilizing thermodynamics relations, such as; $$K_T = K_S (1 + \al...
