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Open AccessPeritumoral edema status of glioblastoma identifies patients reaching long-term disease control with specific progression patterns after tumor resection and high-dose proton boost
Glioblastoma peritumoral edema (PE) extent is associated with survival and progression pattern after tumor resection and radiotherapy (RT). To increase tumor control, proton beam was adopted to give high-dose ...
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Open AccessMaximum resection and immunotherapy improve glioblastoma patient survival: a retrospective single-institution prognostic analysis
Glioblastoma (GBM) is a refractory disease with a poor prognosis and various methods, including maximum resection and immunotherapy, have been tested to improve outcomes. In this retrospective study we analyze...
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Open AccessExercise training using hybrid assistive limb (HAL) lumbar type for locomotive syndrome: a pilot study
With a rapidly aging population in Japan, locomotive syndrome is becoming an increasingly serious social problem. Exercise therapy using the lumbar type HAL, which is a wearable robot suit that can assist volu...
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Open AccessGender-specific analysis for the association between trunk muscle mass and spinal pathologies
We investigated the relationship between trunk muscle mass and spinal pathologies by gender. This multicenter cross-sectional study included patients aged ≥ 30 years who visited a spinal outpatient clinic. Tru...
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Open AccessQuadrigeminal arachnoid cyst with perinatal encephalocele
Quadrigeminal arachnoid cyst (QAC) associated with encephalocele is rare; and while some treatments have been developed in recent years, no definite therapeutic approach for QAC has been established. Endoscopi...
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Open AccessMalignant transformation of pleomorphic xanthoastrocytoma and differential diagnosis: case report
Pleomorphic xanthoastrocytoma (PXA) is a rare astrocytic glioma, characterized by large pleomorphic and frequently multinucleated cells, spindle and lipidized cells, a dense pericellular reticulin network, and...
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Open AccessJCOG0911 INTEGRA study: a randomized screening phase II trial of interferonβ plus temozolomide in comparison with temozolomide alone for newly diagnosed glioblastoma
This study explored the superiority of temozolomide (TMZ) + interferonβ (IFNβ) to standard TMZ as treatment for newly diagnosed glioblastoma (GBM) via randomized phase II screening design.
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Open AccessA case-matched study of stereotactic radiosurgery for patients with brain metastases: comparing treatment results for those with versus without neurological symptoms
We aimed to reappraise whether post-stereotactic radiosurgery (SRS) results for brain metastases differ between patients with and without neurological symptoms. This was an institutional review board-approved,...
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Open AccessEarly clinical experience utilizing scintillator with optical fiber (SOF) detector in clinical boron neutron capture therapy: its issues and solutions
Real-time measurement of thermal neutrons in the tumor region is essential for proper evaluation of the absorbed dose in boron neutron capture therapy (BNCT) treatment. The gold wire activation method has been...
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Open AccessRadiological assessment of shoulder balance following posterior spinal fusion for thoracic adolescent idiopathic scoliosis
The objective of this study was to evaluate shoulder balance following posterior spinal fusion for thoracic adolescent idiopathic scoliosis (AIS).
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Open AccessThe features of degenerative lumbar scoliosis in rheumatoid arthritis patients -matched cohort study
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Open AccessRadiological assessment of shoulder balance following posterior spinal fusion for thoracic adolescent idiopathic scoliosis
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Open AccessRadiographic evaluation of segmental motion of scoliotic wedging segment in degenerative lumbar scoliosis
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Preface to special edition
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Open AccessBMP-2 gene-fibronectin-apatite composite layer enhances bone formation
Safe and efficient gene transfer systems are needed for tissue engineering. We have developed an apatite composite layer including the bone morphogenetic protein-2 (BMP-2) gene and fibronectin (FB), and we evalua...
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Erratum to: Detection of IDH1 mutation in human gliomas: comparison of immunohistochemistry and sequencing
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Lignification and peroxidase in tension wood ofEucalyptus viminalis seedlings
Seedlings ofEucalyptus viminalis were grown for 50 days with their stems bent so tension wood would form. Every 10 days the lignin content, monomeric composition, and peroxidase activity in the tension wood were ...