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  1. Article

    Open Access

    High-dose proton beam therapy versus conventional fractionated radiation therapy for newly diagnosed glioblastoma: a propensity score matching analysis

    High-dose proton beam therapy (PBT) uses excellent dose concentricity based on the unique characteristic termed the Bragg peak. PBT is a highly feasible treatment option that improves survival in select patien...

    Masahide Matsuda, Masashi Mizumoto, Hidehiro Kohzuki, Narushi Sugii in Radiation Oncology (2023)

  2. Article

    Open Access

    Peritumoral edema status of glioblastoma identifies patients reaching long-term disease control with specific progression patterns after tumor resection and high-dose proton boost

    Glioblastoma peritumoral edema (PE) extent is associated with survival and progression pattern after tumor resection and radiotherapy (RT). To increase tumor control, proton beam was adopted to give high-dose ...

    Hsiang-Kuang Tony Liang, Masashi Mizumoto in Journal of Cancer Research and Clinical On… (2021)

  3. Article

    Open Access

    Maximum resection and immunotherapy improve glioblastoma patient survival: a retrospective single-institution prognostic analysis

    Glioblastoma (GBM) is a refractory disease with a poor prognosis and various methods, including maximum resection and immunotherapy, have been tested to improve outcomes. In this retrospective study we analyze...

    Eiichi Ishikawa, Narushi Sugii, Masahide Matsuda, Hidehiro Kohzuki in BMC Neurology (2021)

  4. Article

    Open Access

    Malignant transformation of pleomorphic xanthoastrocytoma and differential diagnosis: case report

    Pleomorphic xanthoastrocytoma (PXA) is a rare astrocytic glioma, characterized by large pleomorphic and frequently multinucleated cells, spindle and lipidized cells, a dense pericellular reticulin network, and...

    Noriyuki Watanabe, Eiichi Ishikawa, Hidehiro Kohzuki, Noriaki Sakamoto in BMC Neurology (2020)