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    Article

    Endoscopic and exoscopic surgery for brain tumors

    Nerves and blood vessels must be protected during brain tumor surgery, which has traditionally relied on microscopes. In the 2000s, endoscopes and related equipment were developed for neurosurgery. In this rev...

    Yasuo Sasagawa, Shingo Tanaka in International Journal of Clinical Oncology (2024)

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    Article

    Optical coherence tomography detects early optic nerve damage before visual field defect in patients with pituitary tumors

    Optical coherence tomography (OCT) is a useful tool for predicting visual recovery after the removal of pituitary tumors. However, the utility of OCT in patients with pituitary tumors and a normal visual field...

    Yasuo Sasagawa, Mitsutaka Nakahara, Daisuke Takemoto in Neurosurgical Review (2023)

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    Article

    Syndrome of inappropriate secretion of antidiuretic hormone as an initial sign of primary central nervous system lymphomas in the hypothalamus

    Primary central nervous system lymphoma (PCNSL) rarely originates in the hypothalamus. Hypothalamic PCNSL can present with various symptoms specific to dysfunction of the hypothalamus, including consciousness ...

    Masahiro Oishi, Yasuhiko Hayashi, Yasuo Sasagawa, Nozomu Oikawa in Acta Neurologica Belgica (2023)

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    Article

    Thyrotropin-secreting pituitary adenomas induce left atrial enlargement with subclinical atrial fibrillation: an echocardiographic study

    Thyrotropin-secreting pituitary adenoma (TSHoma) is rare but occasionally causes cardiovascular complications such as atrial fibrillation (AF) due to hyperthyroidism. Graves' disease (GD) is a common hyperthyr...

    Kenji Yoshiki, Yasuo Sasagawa, Masaya Shimojima, Yumie Takeshita, Sho Takata in Pituitary (2021)

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    Article

    Oculomotor nerve palsy in pituitary apoplexy associated with pituitary adenoma: a radiological analysis with fast imaging employing with steady-state acquisition

    Oculomotor nerve palsy (ONP) occasionally occurs in cases of pituitary apoplexy (PA) associated with pituitary adenoma, but its mechanism remains unclear. Intracranial nerves are clearly visualized by fast-ima...

    Yasuo Sasagawa, Hiroyuki Aburano, Kazumasa Ooiso, Masahiro Oishi in Acta Neurochirurgica (2021)

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    Article

    Radiological and endocrinological evaluations with grading of hypothalamic perifocal edema caused by craniopharyngiomas

    Hypophysial and hypothalamic dysfunction caused by craniopharyngioma is a serious problem despite the progress of surgical approaches and techniques. Perifocal edema induced by craniopharyngioma could be specu...

    Yasuhiko Hayashi, Yasuo Sasagawa, Masahiro Oishi, Kouichi Misaki in Pituitary (2019)

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    Article

    The clinicopathological analysis of receptor tyrosine kinases in meningiomas: the expression of VEGFR-2 in meningioma was associated with a higher WHO grade and shorter progression-free survival

    WHO grade II/III meningiomas recur frequently and there is currently no established molecular target therapy for meningioma. No previous studies have revealed the association between receptor tyrosine kinases ...

    Satoko Nakada, Yasuo Sasagawa, Osamu Tachibana, Hideaki Iizuka in Brain Tumor Pathology (2019)

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    Article

    Radiation-induced gliomas: a report of four cases and analysis of molecular biomarkers

    Radiation-induced glioma (RIG) is a rare secondary glioma. The tumors morphologically resemble their sporadically arising counterparts. Recently, the WHO classification of tumors of the central nervous system ...

    Tsunehito Nakao, Yasuo Sasagawa, Sumihito Nobusawa in Brain Tumor Pathology (2017)

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    Article

    Contribution of sellar dura integrity to symptom manifestation in pituitary adenomas with intratumoral hemorrhage

    Although hemorrhage within pituitary adenomas frequently exacerbates the symptoms, there are many grades of severity. Moreover, the contributing factors for symptom severity are still controversial.

    Yasuhiko Hayashi, Yasuo Sasagawa, Daisuke Kita, Issei Fukui, Masahiro Oishi in Pituitary (2017)

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    Article

    Clinical characteristics of acromegalic patients with empty sella and their outcomes following transsphenoidal surgery

    To analyze the clinical characteristics of acromegalic patients with empty sella (ES, herniation of the subarachnoid space within the sella turcica) and the impact of ES on transsphenoidal surgery in such pati...

    Yasuo Sasagawa, Yasuhiko Hayashi, Osamu Tachibana, Masahiro Oishi, Issei Fukui in Pituitary (2017)

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    Article

    Prediction of postoperative diabetes insipidus using morphological hyperintensity patterns in the pituitary stalk on magnetic resonance imaging after transsphenoidal surgery for sellar tumors

    Diabetes insipidus (DI) remains a complication of transsphenoidal surgery (TSS) for sellar and parasellar tumors. Antidiuretic hormone (ADH) appears as hyper intensity (HI) in the pituitary stalk and the poste...

    Yasuhiko Hayashi, Daisuke Kita, Takuya Watanabe, Issei Fukui, Yasuo Sasagawa in Pituitary (2016)

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    Article

    Carotid artery protrusion and dehiscence in patients with acromegaly

    Acromegaly is a systemic disease which causes multiple bony alterations. Some authors reported that acromegalic patients have risk factors for an intraoperative vascular injury due to the specific anatomical f...

    Yasuo Sasagawa, Osamu Tachibana, Mariko Doai, Yasuhiko Hayashi, Hisao Tonami in Pituitary (2016)

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    Article

    Pediatric symptomatic Rathke cleft cyst compared with cystic craniopharyngioma

    Symptomatic Rathke cleft cysts (RCCs) are rarely detected in neuroradiological screening and are less commonly found in children than in adults. However, when RCCs are observed in children, it is important to ...

    Yasuhiko Hayashi, Daisuke Kita, Issei Fukui, Yasuo Sasagawa in Child's Nervous System (2016)

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    Article

    NAB2–STAT6 fusion gene analysis in two cases of meningeal solitary fibrous tumor/hemangiopericytoma with late distant metastases

    We present two cases of meningeal solitary fibrous tumor (SFT)/hemangiopericytoma (HPC) with immunohistochemistry of STAT6 and analysis of NAB2–STAT6 fusion genes. Case 1 was a 37-year-old male with a left mid...

    Satoko Nakada, Hiroshi Minato, Tsutomu Takegami, Nozomu Kurose in Brain Tumor Pathology (2015)

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    Article

    Median nerve conduction studies and wrist magnetic resonance imaging in acromegalic patients with carpal tunnel syndrome

    Carpal tunnel syndrome (CTS) often occurs with acromegaly; however, the pathophysiology of CTS in acromegalic patients remains unclear. This study evaluated the median nerve in acromegalic patients with and w...

    Yasuo Sasagawa, Osamu Tachibana, Mariko Doai, Hisao Tonami, Hideaki Iizuka in Pituitary (2015)

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    Article

    Diagnostic value of interleukin-10 in cerebrospinal fluid for diffuse large B-cell lymphoma of the central nervous system

    A biomarker for early diagnosis of central nervous system (CNS) lymphoma would permit early treatment for attenuation of disease progression and neurological deterioration. High interleukin-10 (IL-10) or an IL...

    Yasuo Sasagawa, Takuya Akai, Osamu Tachibana, Hideaki Iizuka in Journal of Neuro-Oncology (2015)

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    Article

    Narrow band imaging-guided endoscopic biopsy for intraventricular and paraventricular brain tumors: clinical experience with 14 cases

    Narrow-band imaging (NBI) has been confirmed as a useful endoscopic technique to distinguish neoplasm from normal tissue, on the basis of the enhanced neovascularity of tumor tissue. NBI-guided tissue biopsy f...

    Yasuo Sasagawa, Takuya Akai, Satoko Nakada, Hiroshi Minato in Acta Neurochirurgica (2014)

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    Article

    Internal carotid arterial shift after transsphenoidal surgery in pituitary adenomas with cavernous sinus invasion

    The intercarotid distance (ICD) between cavernous carotid arteries (CCAs) is an important factor for avoiding injury of the internal carotid artery during transsphenoidal surgery. The ICD between CCAs in pitui...

    Yasuo Sasagawa, Osamu Tachibana, Mariko Doai, Takuya Akai, Hisao Tonami in Pituitary (2013)