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  1. No Access

    Article

    BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells

    Long interspersed element-1 (LINE-1, or L1) is the only autonomous retrotransposon that is active in human cells. Different host factors have been shown to influence L1 mobility; however, systematic analyses o...

    Paolo Mita, **aoji Sun, David Fenyö… in Nature Structural & Molecular Biology (2020)

  2. No Access

    Article

    A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors

    A collection of 1,406 high-quality, immunoprecipitation- and immunoblotting-grade monoclonal antibodies to 737 human transcription factors is made available as a community resource, along with all validation d...

    Anand Venkataraman, Kun Yang, Jose Irizarry, Mark Mackiewicz, Paolo Mita… in Nature Methods (2018)

  3. No Access

    Article

    The NIH Protein Capture Reagents Program (PCRP): a standardized protein affinity reagent toolbox

    Seth Blackshaw, Anand Venkataraman, Jose Irizarry, Kun Yang… in Nature Methods (2016)

  4. No Access

    Article

    Tissue matrix arrays for high-throughput screening and systems analysis of cell function

    High-throughput tissue arrays allow for evaluation of in vitro cellular responses and correlation to matrix composition.

    Vince Z Beachley, Matthew T Wolf, Kaitlyn Sadtler, Srikanth S Manda… in Nature Methods (2015)

  5. Article

    Open Access

    RNA-Seq optimization with eQTL gold standards

    RNA-Sequencing (RNA-Seq) experiments have been optimized for library preparation, map**, and gene expression estimation. These methods, however, have revealed weaknesses in the next stages of analysis of dif...

    Shannon E Ellis, Simone Gupta, Foram N Ashar, Joel S Bader, Andrew B West… in BMC Genomics (2013)

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  6. No Access

    Article

    Modeling Intercellular Transfer of Biomolecules Through Tunneling Nanotubes

    Tunneling nanotubes (TNTs) have previosly been observed as long and thin transient structures forming between cells and intercellular protein transfer through them has been experimentally verified. It is hypot...

    Yasir Suhail, Kshitiz, Justin Lee, Mark Walker… in Bulletin of Mathematical Biology (2013)

  7. No Access

    Article

    Human Proteinpedia enables sharing of human protein data

    Suresh Mathivanan, Mukhtar Ahmed, Natalie G Ahn, Hainard Alexandre… in Nature Biotechnology (2008)

  8. No Access

    Article

    Gaining confidence in high-throughput protein interaction networks

    Although genome-scale technologies have benefited from statistical measures of data quality, extracting biologically relevant pathways from high-throughput proteomics data remains a challenge. Here we develop ...

    Joel S Bader, Amitabha Chaudhuri, Jonathan M Rothberg, John Chant in Nature Biotechnology (2004)