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Article
BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells
Long interspersed element-1 (LINE-1, or L1) is the only autonomous retrotransposon that is active in human cells. Different host factors have been shown to influence L1 mobility; however, systematic analyses o...
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Article
A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors
A collection of 1,406 high-quality, immunoprecipitation- and immunoblotting-grade monoclonal antibodies to 737 human transcription factors is made available as a community resource, along with all validation d...
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Article
The NIH Protein Capture Reagents Program (PCRP): a standardized protein affinity reagent toolbox
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Article
Tissue matrix arrays for high-throughput screening and systems analysis of cell function
High-throughput tissue arrays allow for evaluation of in vitro cellular responses and correlation to matrix composition.
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Article
Open AccessRNA-Seq optimization with eQTL gold standards
RNA-Sequencing (RNA-Seq) experiments have been optimized for library preparation, map**, and gene expression estimation. These methods, however, have revealed weaknesses in the next stages of analysis of dif...
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Article
Human Proteinpedia enables sharing of human protein data
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Article
Gaining confidence in high-throughput protein interaction networks
Although genome-scale technologies have benefited from statistical measures of data quality, extracting biologically relevant pathways from high-throughput proteomics data remains a challenge. Here we develop ...