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Article
Analysis of a Combined Filtered/Phase-Field Approach to Topology Optimization in Elasticity
We advance a combined filtered/phase-field approach to topology optimization in the setting of linearized elasticity. Existence of minimizers is proved and rigorous parameter asymptotics are discussed by means...
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Article
Open AccessLumped-parameter model as a non-invasive tool to assess coronary blood flow in AAOCA patients
Anomalous aortic origin of the coronary artery (AAOCA) is a rare disease associated with sudden cardiac death, usually related to physical effort in young people. Clinical routine tests fail to assess the isch...
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Article
Special issue: Numerical simulation for additive manufacturing processes and products
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Article
Open AccessTwo-level method part-scale thermal analysis of laser powder bed fusion additive manufacturing
Numerical simulations of a complete laser powder bed fusion (LPBF) additive manufacturing (AM) process are extremely challenging, or even impossible, to achieve without a radical model reduction of the complex...
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Article
Deep Learning to Automatically Segment and Analyze Abdominal Aortic Aneurysm from Computed Tomography Angiography
Although segmentation of Abdominal Aortic Aneurysms (AAA) thrombus is a crucial step for both the planning of endovascular treatment and the monitoring of the intervention’s outcome, it is still performed manu...
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Open AccessA continuous model for the simulation of manufacturing swarm robotics
Manufacturing large and/or complex structural components is today non-trivial and far-too expensive, due to limitations in the state-of-the-art production processes. Swarm robotics could then bring a different...
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Article
Open AccessA coupled multiphase Lagrangian-Eulerian fluid-dynamics framework for numerical simulation of Laser Metal Deposition process
We present a Computational Fluid Dynamics (CFD) framework for the numerical simulation of the Laser Metal Deposition (LMD) process in 3D printing. Such a framework, comprehensive of both numerical formulations...
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Article
Three-D-printed simulator for kidney transplantation
Three-Dimensional (3D) printing technology can be used to manufacture training platforms for surgeons. Kidney transplantation offers a suitable model, since it mostly entails vascular and ureteric anastomoses.
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Open AccessEarly-age creep behaviour of 3D printable mortars: Experimental characterisation and analytical modelling
The construction sector is experiencing significant technological innovations with digitalisation tools and automated construction techniques, such as additive manufacturing. Additive manufacturing utilising c...
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Open AccessMixed variational formulations for structural topology optimization based on the phase-field approach
We propose a variational principle combining a phase-field functional for structural topology optimization with a mixed (three-field) Hu–Washizu functional, then including directly in the formulation equilibri...
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Article
Open AccessShape fidelity and sterility assessment of 3D printed polycaprolactone and hydroxyapatite scaffolds
Polycaprolactone (PCL) and hydroxyapatite (HA) composite are widely used in tissue engineering (TE). They are fit to being processed with three-dimensional (3D) printing technique to create scaffolds with veri...
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Article
Open AccessGeometric Analysis to Determine Kinking and Shortening of Bridging Stents After Branched Endovascular Aortic Repair
To evaluate bridging stent geometry in patients who underwent branched endovascular aortic repair (B-EVAR) and to correlate the outcomes with intrinsic bridging stent characteristics aiming to identify the ste...
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Article
Automatic Differentiation for Solid Mechanics
Automatic differentiation (AD) is an ensemble of techniques that allows to evaluate accurate numerical derivatives of a mathematical function expressed in a computer programming language. In this paper we use ...
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Article
Open AccessCorrection to: The androgen receptor/filamin A complex as a target in prostate cancer microenvironment
A Correction to this paper has been published: https://doi.org/10.1038/s41419-021-03483-4
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Article
Open AccessThe androgen receptor/filamin A complex as a target in prostate cancer microenvironment
Prostate cancer represents the major cause of cancer-related death in men and patients frequently develop drug-resistance and metastatic disease. Most studies focus on hormone-resistance mechanisms related to ...
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Article
Open AccessNumerical Evaluation of Advanced Laser Control Strategies Influence on Residual Stresses for Laser Powder Bed Fusion Systems
Process-dependent residual stresses are one of the main burdens to a widespread adoption of laser powder bed fusion technology in industry. Residual stresses are directly influenced by process parameters, such...
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Open AccessDiffusion–reaction compartmental models formulated in a continuum mechanics framework: application to COVID-19, mathematical analysis, and numerical study
The outbreak of COVID-19 in 2020 has led to a surge in interest in the research of the mathematical modeling of epidemics. Many of the introduced models are so-called compartmental models, in which the total quan...
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Open Access3D Automatic Segmentation of Aortic Computed Tomography Angiography Combining Multi-View 2D Convolutional Neural Networks
The quantitative analysis of contrast-enhanced Computed Tomography Angiography (CTA) is essential to assess aortic anatomy, identify pathologies, and perform preoperative planning in vascular surgery. To overc...
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Article
Basis of the Lattice Boltzmann Method for Additive Manufacturing
Additive manufacturing (or 3D printing) is constantly growing as an innovative process for the production of complex-shape components. Among the seven recognized 3D printing technologies, powder bed fusion (PB...
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Article
Feasibility of 3D printed salivary duct models for sialendoscopic skills training: preliminary report
To explore the feasibility of 3D printed salivary duct models for the sialendoscopic skills training.