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  1. No Access

    Article

    Future projections of the surface heat and water budgets of the Mediterranean Sea in an ensemble of coupled atmosphere–ocean regional climate models

    Within the CIRCE project “Climate change and Impact Research: the Mediterranean Environment”, an ensemble of high resolution coupled atmosphere–ocean regional climate models (AORCMs) are used to simulate the M...

    C. Dubois, S. Somot, S. Calmanti, A. Carillo, M. Déqué, A. Dell’Aquilla in Climate Dynamics (2012)

  2. No Access

    Article

    Immunodetection of inactivated Francisella tularensis bacteria by using a quartz crystal microbalance with dissipation monitoring

    Francisella tularensis are very small, gram-negative bacteria which are capable of infecting a number of mammals. As a highly pathogenic species, it is a potential bioterrorism agent. In this wor...

    K. Kleo, D. Schäfer, S. Klar, D. Jacob, R. Grunow in Analytical and Bioanalytical Chemistry (2012)

  3. Article

    Open Access

    The spread amongst ENSEMBLES regional scenarios: regional climate models, driving general circulation models and interannual variability

    Various combinations of thirteen regional climate models (RCM) and six general circulation models (GCM) were used in FP6-ENSEMBLES. The response to the SRES-A1B greenhouse gas concentration scenario over Europ...

    M. Déqué, S. Somot, E. Sanchez-Gomez, C. M. Goodess, D. Jacob in Climate Dynamics (2012)

  4. No Access

    Article

    Extremes and predictability in the European pre-industrial climate of a regional climate model

    A high-resolution pre-industrial control simulation with the regional climate model REMO is analyzed in detail for different European subregions. To our knowledge, this is the first long pre-industrial control...

    L. Tomassini, S. Hagemann, Ch. Moseley, A. Haumann, R. Podzun, D. Jacob in Climate Dynamics (2011)

  5. No Access

    Article

    The transcription factor GATA-1 is overexpressed in breast carcinomas and contributes to survivin upregulation via a promoter polymorphism

    Expression of survivin, a member of the inhibitor of apoptosis protein family, is elevated in human cancers and considered as a new therapeutic target. Mechanism upregulating survivin expression in tumour cell...

    R Boidot, F Végran, D Jacob, S Chevrier, M Cadouot, O Feron, E Solary in Oncogene (2010)

  6. Article

    Open Access

    Downscaling extreme month-long anomalies in southern South America

    We investigate the performance of one stretched-grid atmospheric global model, five different regional climate models and a statistical downscaling technique in simulating 3 months (January 1971, November 1986...

    C. G. Menéndez, M. de Castro, J.-P. Boulanger, A. D’Onofrio, E. Sanchez in Climatic Change (2010)

  7. No Access

    Chapter and Conference Paper

    A Scalable Process for Helper-Dependent Adenoviral Vector Production Using PEI-Derived Transfection Strategy in Suspension Culture

    Helper-dependent adenoviral vector has demonstrated a high therapeutic potential; however, the poor efficiency of the actual production process hampers further large-scale clinical evaluation. In this work, we...

    E. Dormond, A. Meneses-Acosta, D. Jacob, Y. Durocher, M. Perrier in Cells and Culture (2010)

  8. No Access

    Chapter and Conference Paper

    Inhibition of Sonic Hedgehog signaling reduces tumor growth in pancreatic cancer in vitro and in vivo

    Introduction: Activation of the hedgehog signal transduction pathway, triggered by hedgehog binding to the transmembrane receptor PTCH or by mutations in the PTCH gene, plays an important role in...

    Priv.-Doz. Dr. M. Bahra, U. P. Neumann, D. Jacob in Chirurgisches Forum und DGAV Forum 2009 (2009)

  9. Article

    Open Access

    Sensitivity of climate models to seasonal variability of snow-free land surface albedo

    The seasonal variation of snow-free land surface albedo was integrated into the land surface schemes of the global climate model ECHAM5 and the regional climate model REMO to test the sensitivity of climate mo...

    D. Rechid, S. Hagemann, D. Jacob in Theoretical and Applied Climatology (2009)

  10. No Access

    Article

    Metastasen im Pankreas

    Der Stellenwert der Resektion von Pankreasmetastasen ist bisher nicht hinreichend untersucht. Wir untersuchten unser Patientengut nach Pankreasresektionen bei Metastasen im Pankreas retrospektiv hinsichtlich d...

    Dr. M. Bahra, D. Jacob, J.M. Langrehr, M. Glanemann, G. Schumacher in Der Chirurg (2008)

  11. Article

    Open Access

    An evaluation of Arctic cloud and radiation processes during the SHEBA year: simulation results from eight Arctic regional climate models

    Eight atmospheric regional climate models (RCMs) were run for the period September 1997 to October 1998 over the western Arctic Ocean. This period was coincident with the observational campaign of the Surface ...

    K. Wyser, C. G. Jones, P. Du, E. Girard, U. Willén, J. Cassano in Climate Dynamics (2008)

  12. No Access

    Chapter and Conference Paper

    Characterization of a (021) twin in coesite using LACBED and precession electron diffraction

    Coesite is a high-pressure polymorph of silica stable in the pressure range 2.5–9 GPa, which corresponds to a minimum depth in Earth of ca. 90 km. Given the ubiquity of silica at the surface of the Earth, coes...

    P. Cordier, D. Jacob, H. -P. Schertl in EMC 2008 14th European Microscopy Congress… (2008)

  13. No Access

    Chapter and Conference Paper

    Electron precession characterization of pseudo-merohedral twins in the LaGaO3 perovskite

    Pseudo-merohedric twins are frequently observed in the orthorhombic LaGaO3 perovskite [1] because this perovskite displays some very small symmetry departures from an ideal cubic ABO3 perovskite. The characteriza...

    G. Ji, J. P. Morniroli, G. J. Auchterlonie in EMC 2008 14th European Microscopy Congress… (2008)

  14. No Access

    Chapter and Conference Paper

    Contribution of electron precession to the study of crystals displaying small symmetry departures

    Many crystals display some small symmetry departures from a high symmetry. For example, a crystal has a tetragonal or an orthorhombic structure very close to a cubic structure. In this case, many zone axis ele...

    J. P. Morniroli, G. Ji, D. Jacob in EMC 2008 14th European Microscopy Congress… (2008)

  15. No Access

    Chapter and Conference Paper

    Precession Electron Diffraction for the characterization of twinning in pseudo-symmetrical crystals: case of coesite

    Recent developments in electron diffraction call for a reappraisal of the possibilities offered by spot patterns. Among them is the Vincent-Midgley Precession Electron Diffraction (PED) technique [1], which re...

    D. Jacob, P. Cordier, J. P. Morniroli in EMC 2008 14th European Microscopy Congress… (2008)

  16. No Access

    Chapter and Conference Paper

    TEM study of Comet Wild 2 pyroxene particles collected during the stardust mission

    In January 2006, the NASA Stardust spacecraft successively returned to Earth dust from comet 81P/Wild 2, captured in a low-density SiO2 aerogel. Samples of three collected pyroxene-rich particles have been invest...

    D. Jacob, J. Stodolna, H. Leroux in EMC 2008 14th European Microscopy Congress… (2008)

  17. No Access

    Article

    Ultrasound imaging of non-traumatic lesions of wrist and hand tendons

    Non-traumatic tendon lesions are common and diverse at the wrist and hand. Improvements in high-resolution ultrasound (US) are producing increasingly high-quality images of superficial structures, thus expandi...

    D. Jacob, M. Cohen, S. Bianchi in European Radiology (2007)

  18. No Access

    Article

    An intercomparison of regional climate simulations for Europe: assessing uncertainties in model projections

    Ten regional climate models (RCM) have been integrated with the standard forcings of the PRUDENCE experiment: IPCC-SRES A2 radiative forcing and Hadley Centre boundary conditions. The response over Europe, cal...

    M. Déqué, D. P. Rowell, D. Lüthi, F. Giorgi, J. H. Christensen in Climatic Change (2007)

  19. Article

    Evaluation of an ensemble of Arctic regional climate models: spatiotemporal fields during the SHEBA year

    A. Rinke, K. Dethloff, J. J. Cassano, J. H. Christensen, J. A. Curry in Climate Dynamics (2006)

  20. No Access

    Article

    Evaluation of an ensemble of Arctic regional climate models: spatiotemporal fields during the SHEBA year

    Simulations of eight different regional climate models (RCMs) have been performed for the period September 1997–September 1998, which coincides with the Surface Heat Budget of the Arctic Ocean (SHEBA) project ...

    A. Rinke, K. Dethloff, J. J. Cassano, J. H. Christensen, J. A. Curry in Climate Dynamics (2006)

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