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Co-ReaSON: EEG-based Onset Detection of Focal Epileptic Seizures with Multimodal Feature Representations
Early detection of an epileptic seizure’s onset is crucial to reduce the impact of seizures on the patient’s health. The Electroencephalogram (EEG)... -
Efficacy and Tolerability of Adjunctive Brivaracetam in Patients with Focal-Onset Seizures on Specific Concomitant Antiseizure Medications: Pooled Analysis of Double-Blind, Placebo-Controlled Trials
IntroductionThis article aimed to assess the efficacy and tolerability of adjunctive brivaracetam (BRV) in adults with focal-onset seizures on...
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Efficacy and tolerability of lacosamide as adjunctive therapy in patients with focal-onset seizures: an observational, prospective study
PurposeTo evaluate the efficacy and tolerability of adjunctive lacosamide (LCM) in patients with focal-onset seizures, with or without combined...
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Effect of Cenobamate on Cognition in Patients with Drug-Resistant Epilepsy with Focal Onset Seizures: An Exploratory Study
Background and ObjectiveMost second and third generation antiseizure medications (ASMs) are associated with cognitive adverse events, which are a...
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Using a standalone ear-EEG device for focal-onset seizure detection
BackgroundSeizure detection is challenging outside the clinical environment due to the lack of comfortable, reliable, and practical long-term...
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Effectiveness and Safety of Adjunctive Cenobamate in People with Focal-Onset Epilepsy: Evidence from the First Interim Analysis of the BLESS Study
IntroductionDespite new anti-seizure medications (ASMs) being introduced into clinical practice, about one-third of people with epilepsy do not reach...
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Third-Generation Antiseizure Medications for Adjunctive Treatment of Focal-Onset Seizures in Adults: A Systematic Review and Network Meta-analysis
BackgroundBrivaracetam (BRV), cenobamate (CNB), eslicarbazepine acetate (ESL), lacosamide (LCM) and perampanel (PER) are antiseizure medications...
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Sudden Onset Focal Neurology: A Cardiac Cause
An 86 year-old female presented acutely to the regional stroke centre with aphasia and right-sided weakness. In the department, her neurology... -
Absence seizures in lesion-related epilepsy
BackgroundIn the new International League Against Epilepsy (ILAE) classification of seizure types, generalized seizures such as absence seizures...
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Seizures
A brief introduction to the pathology of epilepsy is presented. Seizure-prone areas of the brain are always accompanied by reactive gliosis. These... -
Stroke-related early seizures: clinical and neurophysiological study in a sample of Egyptian population
BackgroundAvailable data collected from patients of different types of acute cerebrovascular strokes can detect risk factors, clinical data...
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Eslicarbazepine Acetate: A Review in Focal-Onset Seizures
Eslicarbazepine acetate (Zebinix ® ), a voltage-gated sodium channel blocker, is a once-daily, orally administered anti-seizure medication available in...
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Treatment of Seizures in the Neonate: Special Report From the ILAE Task Force on Neonatal Seizures, 2022
The International League Against Epilepsy (ILAE) task force on neonatal seizures has recently published draft guidelines and consensus-based...
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Withdrawal seizures vs on-medication seizures: an intracranial EEG recording case report
BackgroundIt has long been an interesting question of whether withdrawal seizures in epileptic patients differ from habitual seizures in terms of...
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Vestibular seizures and spontaneous downbeat nystagmus of ganglioglioma origin: a case report
BackgroundLow-grade gangliogliomas (GGs) are typically epileptogenic intracranial neoplasms. Yet, the presentation of simplex vertiginous experience...
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Safety and Efficacy of Ketamine Without Intubation in the Management of Refractory Seizures: A Case Series
BackgroundContinuous infusion ketamine has demonstrated efficacy in the management of refractory seizures yet does not suppress respiratory drive...
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A Prospective Longitudinal Study of the Effects of Eslicarbazepine Acetate Treatment on Bone Density and Metabolism in Patients with Focal-Onset Epilepsy
Background and objectivesEslicarbazepine acetate (ESL) is a third-generation anti-seizure medication for patients with focal-onset epilepsy. There...
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Acute Symptomatic Seizures and Risk of Seizure Recurrence in Patients with Anti-NMDAR, Anti-LGI1, and Anti-GABABR Encephalitis
AimsTo analyze the clinical characteristics of acute symptomatic seizures and predict the risk factors for seizure recurrence in patients with...
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Predictive factors for post operative seizures following meningioma resection in patients without preoperative seizures: a multicenter retrospective analysis
PurposeMeningiomas are the most common primary brain tumor and represent 35% of all intracranial neoplasms. However, in the early post-operative...
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