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Tailoring the Microenvironment of Cells Towards Osteogenic Differentiation Using Multilayers of Glycosaminoglycans and Growth Factor Immobilization
The extracellular matrix (ECM) provides the structural support and signals important for cell fate, tissue homeostasis and regeneration....
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Acrylamide-based hydrogels with distinct osteogenic and chondrogenic differentiation potential
Regeneration solutions for the osteochondral interface depth are limited, where multi-material implants have the potential to delaminate affecting...
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Ternary MXene-loaded PLCL/collagen nanofibrous scaffolds that promote spontaneous osteogenic differentiation
Conventional bioinert bone grafts often have led to failure in osseointegration due to low bioactivity, thus much effort has been made up to date to...
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Single-Dose Induction of Osteogenic Differentiation of Mesenchymal Stem Cells Using a Cyclic AMP Activator, Forskolin
AbstractSmall molecule-based bone regenerative engineering has been proposed as a promising approach in repairing bone tissue and circumventing the...
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Electrically controlled mRNA delivery using a polypyrrole-graphene oxide hybrid film to promote osteogenic differentiation of human mesenchymal stem cells
Direct messenger ribonucleic acid (mRNA) delivery to target cells or tissues has revolutionized the field of biotechnology. However, the...
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Enhanced osteogenic differentiation of alendronate-conjugated nanodiamonds for potential osteoporosis treatment
BackgroundAlendronate (Alen) is promising material used for bone-targeted drug delivery due to its high bone affinity and therapeutic effects on bone...
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Black Phosphorus Nanoparticles Promote Osteogenic Differentiation of EMSCs Through Upregulated TG2 Expression
At bio-safe concentrations, black phosphorus nanoparticles activated TG2, and promote the expression of ECM, which further promoted osteogenic...
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Sustainably releasing osteogenic trace elements from montmorillonite intercalated hybrid nanocomposites accelerates bone regeneration
Optimizing scaffold components and architectures to achieve endogenous osteogenesis is a prospective advancement for bone tissue engineering. Here,...
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3D printed OCP bone scaffold with alginate enhancing osteogenic differentiation in MG-63 cells
3D printing technology using calcium phosphate materials such as octacalcium phosphate (OCP, Ca 8 H 2 [PO 4 ] 6 ·5H 2 O) has emerged as a precise approach for...
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Plasma Electrolytic Oxidation (PEO) Coated CP-Ti: Wear Performance on Reciprocating Mode and Chondrogenic–Osteogenic Differentiation
Biocompatible oxide coatings obtained by plasma electrolyte oxidation (PEO) have been used to improve the surface properties of bone grafts made of...
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Monocytes and pyrophosphate promote mesenchymal stem cell viability and early osteogenic differentiation
Pyrophosphate-containing calcium phosphate implants promote osteoinduction and bone regeneration. The role of pyrophosphate for inflammatory...
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Osteogenic differentiation of rat bone mesenchymal stem cells cultured on poly (hydroxybutyrate-co-hydroxyvalerate), poly (ε-caprolactone) scaffolds
Bioresorbable biomaterials can fill bone defects and act as temporary scaffold to recruit MSCs to stimulate their differentiation. Among the...
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Enhancing osteogenic bioactivities of coaxial electrospinning nano-scaffolds through incorporating iron oxide nanoparticles and icaritin for bone regeneration
Bone tissue engineering provides a promising strategy for the treatment of bone defects. Nonetheless, the clinical utilization of biomaterial-based...
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Poly(dopamine)-assisted Bioactive Coating on the Surface of Porous Poly (Ether Ether Ketone) to Promote Osteogenic Differentiation of rBMSC
A facile modification strategy is developed to promote the proliferation and osteogenic differentiation of rat bone marrow stromal cells (rBMSCs)...
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Antibacterial wollastonite supported excellent proliferation and osteogenic differentiation of human bone marrow derived mesenchymal stromal cells
Biocompatibility and bacterial infections are the primary concerns associated with the current bone graft substitutes. The application of...
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Effect of dexamethasone as osteogenic supplementation in in vitro osteogenic differentiation of stem cells from human exfoliated deciduous teeth
In in vitro culture systems, dexamethasone (DEX) has been applied with ascorbic acid (ASC) and β-glycerophosphate (βGLY) as culture media...
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Silk sericin-hydroxyapatite nanoribbons toward structurally stable osteogenic scaffolds
Building a successful, cost-effective, and natural solution toward improving the bone-implant interface is an outstanding challenge. Silkworm sericin...
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Osteogenic Properties of Titanium Alloy Ti6Al4V-Hydroxyapatite Composites Fabricated by Selective Laser Melting
Hydroxyapatite (HA) has been widely used for coating metal bone implants. However, HA coating may separate from the metal substrates, resulting in...
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ZnO-NPs-Coated Implants with Osteogenic Properties for Enhanced Osseointegration
The failure of orthopedic implantsImplant due to prosthesis-associated infections and aseptic loosening emphasizes the pressing need to enhance their...
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Improved drug incorporation and in vitro osteogenic effect of baicalin coating on different modified titanium surfaces
Poor osseointegration has been regarded as a cause of implant failure in the early stage of healing. Baicalin (BC) is a flavonoid that can promote...
