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Structure of human spermine oxidase in complex with a highly selective allosteric inhibitor
Human spermine oxidase (hSMOX) plays a central role in polyamine catabolism. Due to its association with several pathological processes, including...
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Rhizobacteria control dam**-off and promote growth of lima bean with and without co-inoculation with Rhizobium tropici CIAT899
Rhizoctonia solani compromises the production of lima bean, an alternative and low-input food source in many tropical regions. Inoculation of...
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A Comprehensive Review on Enhanced Biohydrogen Production: Pretreatment, Applied Strategies, Techno-Economic Assessment, and Future Perspective
In the direction of sustainable and zero carbon energy production, hydrogen is considered as a potential fuel with high heating value and energy...
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USP1 promotes cholangiocarcinoma progression by deubiquitinating PARP1 to prevent its proteasomal degradation
Despite its involvement in various cancers, the function of the deubiquitinase USP1 (ubiquitin-specific protease 1) is unexplored in...
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Hyaluronan in mesenchymal stromal cell lineage differentiation from human pluripotent stem cells: application in serum free culture
BackgroundHyaluronan (HA) is an extracellular glycosaminoglycan polysaccharide with widespread roles throughout development and in healthy and...
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Climate change and the growth of Amazonian species seedlings: an ecophysiological approach to Euterpe oleracea
Climate change threatens many native species from the Amazon Forest. Among the endangered species is the Açaí ( Euterpe oleracea ), which is a species...
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Microbial Pigments and Paints for Clean Environment
Microbial pigments, due to their several beneficial properties, are increasingly gaining attention in various industries such as nutraceutical,...
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Biohydrogen from Fruit and Vegetable Industry Wastes
Hydrogen gas produced during the microbial fermentation of organic materials is termed biohydrogen. It possesses higher energy in comparison to...
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Activity and stability of lipase from Candida Antarctica after treatment in pressurized fluids
Lipase B from Candida antarctica (CalB) is one of the biocatalysts most used in organic synthesis due to its ability to act in several medium, wide...
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Polyethylene degradation and assimilation by the marine yeast Rhodotorula mucilaginosa
Ocean plastic pollution is a severe environmental problem but most of the plastic that has been released to the ocean since the 1950s is unaccounted...
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Efficient production of 14α-OH-AD by engineered Mycolicibacterium neoaurum via coupled cofactor and reconstructed electron transport system
14α-hydroxy-androst-4-ene-3,17-dione (14α-OH-AD) is an important precursor for the synthesis of steroid drugs with anti-cancer and carcinolytic...
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DUOX1 and DUOX2, DUOXA1 and DUOXA2
DUOX1 and DUOX2 constitute a subgroup of long (~1500 amino acids) seven transmembrane domain NADPH oxidases. In addition to the catalytic core common...
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Characterisation of acetogen formatotrophic potential using Eubacterium limosum
AbstractFormate is a promising energy carrier that could be used to transport renewable electricity. Some acetogenic bacteria, such as Eubacterium...
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Effect of micro-aeration on syntrophic and methanogenic activity in anaerobic sludge
AbstractMicro-aeration was shown to improve anaerobic digestion (AD) processes, although oxygen is known to inhibit obligate anaerobes, such as...
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Evaluation of biotransformation capacity of transplastomic plants and hairy roots of Nicotiana tabacum expressing human cytochrome P450 2D6
Cytochrome P450 monooxygenases (CYPs) are important tools for regio- and stereoselective oxidation of target molecules or engineering of metabolic...
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The inner nuclear membrane protein Lem2 coordinates RNA degradation at the nuclear periphery
Transcriptionally silent chromatin often localizes to the nuclear periphery. However, whether the nuclear envelope (NE) is a site for...
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Catalytic role of histidine-114 in the hydrolytic dehalogenation of chlorothalonil by Pseudomonas sp. CTN-3
Chlorothalonil (2,4,5,6-tetrachloroisophthalonitrile; TPN) is an environmentally persistent fungicide that sees heavy use in the USA and is highly...
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Construction and optimization of boldenone synthesis from androstenedione catalyzed by a dual-enzyme system
Boldenone is a protein-assimilating androgen steroid that can promote protein synthesis, support nitrogen storage, and enhance renal erythropoietin...
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Engineering Escherichia coli for a high yield of 1,3-propanediol near the theoretical maximum through chromosomal integration and gene deletion
AbstractGlycerol dehydratase ( gdrAB-dhaB123 ) operon from Klebsiella pneumoniae and NADPH-dependent 1,3-propanediol oxidoreductase ( yqhD ) from Escheric...
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E3 ligase TRIM65 alleviates intestinal ischemia/reperfusion injury through inhibition of TOX4-mediated apoptosis
Intestinal ischemia-reperfusion (II/R) injury is an urgent clinical disease with high incidence and mortality, and impaired intestinal barrier...
