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LC–MS/MS analysis of pyrrolizidine alkaloids in bee bread and commercial pollen from Brazil
Beehive products, particularly pollen, are among the foodstuffs that may contain pyrrolizidine alkaloids (PAs), prompting concern due to their...
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Determination of Pyrrolizidine Alkaloids in Plants, Pollen, and Honey by LC-ESI-MS/MS
This chapter presents a diluted-and-shot sample preparation approach for honey and solid-liquid extraction for pollen and bee plant samples to...
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A sensitive LC–MS/MS method for isomer separation and quantitative determination of 51 pyrrolizidine alkaloids and two tropane alkaloids in cow’s milk
1,2-Unsaturated pyrrolizidine alkaloids (PA), their corresponding N -oxides (PANO), and tropane alkaloids (TA) are toxic secondary plant metabolites....
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Alkaloids in food: a review of toxicity, analytical methods, occurrence and risk assessments
Alkaloids have been utilized by humans for years. They have diverse applications in pharmaceuticals. They have been proven to be effective in...
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Important Contaminants (Mycotoxins, Pesticide Residues, Pirolizidine Alkaloids) in Pollen
Bee pollen is a natural apicultural product that is becoming popular among health-conscious consumers due to its wide variety of nutrients and...
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Pyrrolizidine Alkaloids from Pardoglossum cheirifolium
The ethanolic extract derived from the whole plant of Pardoglossum cheirifolium was submitted to phytochemical investigation. A new pyrrolizidine...
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Synthesis of pyrrolizidine derivatives (microreview)
The review summarizes the methods of synthesis of pyrrolizidine (hexahydro-1 H -pyrrolizine) derivatives published in the literature over the past five...
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Development and validation of an LC-HRMS method for the determination of pyrrolizidine alkaloids and quinolones in honey employing a simple alkaline sample dilution
Honey residue and contaminant assessments are extremely important, as they deal with food and therapeutic safety issues of a widely consumed animal...
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Classification of Diverse Novel Alkaloids
Plants have proved to be a rich and important source of a huge number of new skeleton alkaloids with a large variety of chemical structures and...
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Alkaloids in Diet
Food is one of the three basic requirements of mankind, supplying six kinds of nutrients including water, carbohydrate, protein, lipid, vitamins, and...
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A LC–ESI–MS/MS analysis procedure coupled with solid phase extraction and MeOH extraction method for determination of pyrrolizidine alkaloids in Tussilago farfara and Lithospermi erythrorhzion
Pyrrolizidine alkaloids (PAs) that are plant toxin naturally produced for protection against herbivores in some plant families. They are associated...
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Fluorescent lateral flow immunoassay based on gold nanocluster for detection of pyrrolizidine alkaloids
An ultrasensitive and rapid fluorescent immunoassay based on a broad-spectrum monoclonal antibody (mAb) was developed to detect pyrrolizidine...
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Alkaloids: A Suitable Precursor for Nanomaterials Synthesis, and Their Various Applications
Green chemistry refers to creating chemical products and methods that minimize or avoid producing harmful chemicals. In recent years, natural...
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Biological and Ecological Roles of Club Mosses (Lycopodiaceae) Alkaloids
This paper is a critical overview of studies concerning the Lycopodium alkaloids and presentation of hypotheses that address the biological purpose...
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Development of a new LC-MS method for accurate and sensitive determination of 33 pyrrolizidine and 21 tropane alkaloids in plant-based food matrices
Setting of maximum limits for a number of plant alkaloids is under discussion in the EU. The novel method developed and optimized in this study...
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Interplay of transcription factors orchestrating the biosynthesis of plant alkaloids
Plants produce a range of secondary metabolites primarily as defence molecules. A plant has to invest considerable energy to synthesise alkaloids,...
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A new approach for the thermal characterization of monocrotaline, a pyrrolizidine alkaloid
Monocrotaline (MCT) is a bioactive pyrrolizidine alkaloid (PAs) isolated from Crotalaria retusa seeds. The PAs when taken orally may be toxic to...
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A pyridoxal 5′-phosphate-dependent Mannich cyclase
Pyridoxal 5′-phosphate (PLP)-dependent enzymes catalyse a diverse range of chemical transformations. Despite their extraordinary functional...
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Natural Inflammatory Molecules in Fruits and Vegetables: Alkaloids, Uric Acid, and Fructose
Out of several energy-rich organic compounds formed via photosynthesis in autotrophic organisms like plants, a few of them might prove inflammatory...