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Development of Components of Prolonged Action Antibacterial Dosage Forms Using SCF Technologies
Gentamicin and levofloxacin are encapsulated into bioresorbable polymer scaffolds and microparticles by the SCF methods: particles from gas saturated...
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Structural and probing dynamics of Brij-35-based microemulsion for fluoroquinolone antibiotics
In this study, an oil-in-water microemulsion (µE) formulation was developed using clove oil/Brij-35/isopropanol/water to solubilize fluoroquinolone...
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Synthesis, characterization, antimicrobial and antifungal activity studies of two novel aminopyridine−sulfamoylbenzoic acid salts and their Cu(II) complexes
Two new proton transfer compounds, (H2a3mp) + (psba) − ( 1 ) and (H2a3mp) + (2MeO5sba) − ( 2 ), obtained from 2-amino-3-methylpyridine with (2a3mp) and...
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Materials Technology and Its Advancements Involving Nanotechnology, Hydrogels, and Its Impact Assessment on Various Aspects of Improving the Healthcare System
In recent years, materials technology has experienced remarkable progress, especially in the fields of nanotechnology and hydrogels. Nanotechnology,... -
Drug Delivery to Diseases Caused by E. coli Infection
The Escherichia coli are one of the most common facultative anaerobe in the intestinal tract of humans and many other endothermic species. Mostly,... -
Rapid Detection of Quinolone Antibiotics in Aquatic Products by Surface-Enhanced Raman Spectroscopy Combined with Thin Layer Chromatography
AbstractThis study presents the establishment of surface-enhanced Raman spectroscopy ( SERS ) combined with the thin-layer chromatography ( TLC ) method...
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Tuberculosis and Drug Delivery System: Clinical Trials in TB
Tuberculosis (TB) is a communicable disease caused by the bacterium Mycobacterium tuberculosis which is the second most lethal infectious disease... -
Voltammetric determination of levofloxacin using silver nanoparticles deposited on a thin nickel oxide porous film
The authors describe a simplified chemical precipitation method and silver mirror reaction to synthesize a nanocomposite consiting of silver...
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Manufacturer Identification and Active Ingredient Determination of Medicinal Products by Smartphone-Based Near-IR Colorimetry
AbstractA nondestructive method for the analysis of pharmaceuticals (nonsteroidal anti-inflammatory drugs, fluoroquinolones, acetylsalicylic acid,...
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Construction of NH2-MIL-101(Fe) /TiO2 Heterojunction to Enhance the Charge Transfer in Photocatalytic Degradation of Antibiotics
As an indispensable medicine, antibiotics are widely used in daily life, but following the substantial discharge of various wastewater, which result...
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Prevalence of Antimicrobial Resistance Among the Hydrogen Sulfide Producing Bacteria Isolated on XLD Agar from the Poultry Fecal Samples
Poultry products remain as one of the most popular and extensively consumed foods in the world and the introduction of hydrogen sulfide (H 2 S)...
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Nanoobjects for the Luminescence Determination of Fluoroquinolones
AbstractFluoroquinolones are the most successful antibiotics, which also show antiviral and antitumor activity. The widespread use of...
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Green-synthesized Cu2O nanoaggregates incorporated on β-cyclodextrin for catalytic reduction and electrochemical sensing
AbstractMicrowave-assisted methods are facile synthetic routes for the synthesis of nanoparticles. Cu 2 O nanoaggregates (Cu 2 O NA) were synthesized...
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Magnetic Solid-Phase Extraction and Fluorimetric Determination of Some Fluoroquinolones
AbstractAn approach to estimating the concentration of fluoroquinolones based on their sorption and preconcentration by magnetic solid-phase...
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Biomass-derived carbon dots as a sensitive and selective dual detection platform for fluoroquinolones and tetracyclines
A novel carbon dot (CD) was synthesized through the facile and simple hydrothermal method from Curcuma amada , as the precursor for the first time....
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UV Spectroscopic Method for Optimization and Determination of Glibenclamide in Bulk, Pharmaceutical Dosage Form and its Application for In Vitro Interaction Studies
A simple, easy and cost-efficient UV spectroscopic method was developed and validated for glibenclamide, the second generation of sulfonylureas,...
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Spectroscopic studies on the drug–drug interaction: the influence of fluoroquinolones on the affinity of tigecycline to human serum albumin and identification of the binding site
AbstractConcomitant use of two or more drugs in therapy is becoming a more frequent phenomenon and clinically relevant drug–drug interactions at the...
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Synthesis, characterization, and in vitro antibacterial activity of some new pyridinone and pyrazole derivatives with some in silico ADME and molecular modeling study
A new series of pyridine-2-one and pyrazole derivatives were designed and synthesized based on cyanoacrylamide derivatives containing 2,4-dichlro...
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Design, synthesis, and biological investigation of quinoline/ciprofloxacin hybrids as antimicrobial and anti-proliferative agents
Ciprofloxacin-Piperazine C-7 linked quinoline derivatives 6a–c and 8a–c were synthesized and investigated for their antibacterial, antifungal, and...