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Communication in miRNAs Between Inflammation and Cancer
Inflammatory and immune responses are controlled by microRNAs (miRNAs), and cancer is also regulated by miRNAs. Computing analysis and evidence from... -
Diagnostic, Prognostic and Theranostic Potential of miRNAs in Prostate Cancer
A novel class of gene regulators, small noncoding RNAs or microRNAs (miRNAs) has an important role in various malignancies, including prostate cancer... -
Deep Learning of miRNAs for Therapeutic Applications
The RNA Precious Medical Initiative requires a safe, affordable, and sustainable device as an administration tool. Why do microRNA (miRNA) quantum... -
miRNAs in pancreatic cancer progression and metastasis
Small non-coding RNA or microRNA (miRNA) are critical regulators of eukaryotic cells. Dysregulation of miRNA expression and function has been linked...
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Understanding the multifaceted role of miRNAs in Alzheimer’s disease pathology
Small non-coding RNAs (miRNAs) regulate gene expression by binding to mRNA and mediating its degradation or inhibiting translation. Since miRNAs can...
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HPV16-miRNAs exert oncogenic effects through enhancers in human cervical cancer
BackgroundCervical cancer is a human papillomavirus (HPV)-related disease. HPV type 16 (HPV16), which is the predominant cause of cervical cancer,...
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CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines
BackgroundGenome-wide functional screening using the CRISPR-Cas9 system is a powerful tool to uncover tumor-specific and common genetic dependencies...
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Differential Expression of miRNAs in Amyotrophic Lateral Sclerosis Patients
Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease that affects nerve cells in the brain and spinal cord, causing loss of...
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Retro-miRs: novel and functional miRNAs originating from mRNA retrotransposition
BackgroundReverse-transcribed gene copies (retrocopies) have emerged as major sources of evolutionary novelty. MicroRNAs (miRNAs) are small and...
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MiRNAs as potential therapeutic targets and biomarkers for non-traumatic intracerebral hemorrhage
Non-traumatic intracerebral hemorrhage (ICH) is the most common type of hemorrhagic stroke, most often occurring between the ages of 45 and 60....
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Identification and Characterization of Evolutionary Conserved Muskmelon Non-coding miRNAs and Their Target Proteins
MicroRNAs (miRNAs) are short, endogenously encoded small RNAs, 18–26 nucleotides in length, which can posttranscriptionally regulate gene expression...
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From diagnosis to resistance: a symphony of miRNAs in pheochromocytoma progression and treatment response
Pheochromocytoma (PCC) is a neuroendocrine tumor that produces and secretes catecholamine from either the adrenal medulla or extra-adrenal locations....
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miRNAs: possible regulators of toll like receptors and inflammatory tumor microenvironment in colorectal cancer
BackgroundColorectal cancer (CRC) is ranked as the third most commonly diagnosed cancer and the third cause of cancer related deaths. CRC is greatly...
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miRNAs contributing to the repair of tendon injury
Tendon injury is one of the most common disorders of the musculoskeletal system, with a higher likelihood of occurrence in elderly individuals and...
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Screening and identification of specific cluster miRNAs in N2a cells infected by H7N9 virus
This study aims to screen and identify specific cluster miRNAs of H7N9 virus-infected N2a cells and explore the possible pathogenesis of these...
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A Potential Immune-Related miRNAs Regulatory Network and Corresponding Diagnostic Efficacy in Schizophrenia
PurposeImmune-related pathways actively participate in the progression of schizophrenia (SCZ), however, roles of immune-related miRNAs in SCZ are...
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The role of exosome derived miRNAs in inter-cell crosstalk among insulin-related organs in type 2 diabetes mellitus
Exosomes are small extracellular vesicles secreted by almost all cell types, and carry diverse cargo including RNA, and other substances. Recent...
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Expression Patterns of miRNAs in Egyptian Children with ADHD: Clinical Study with Correlation Analysis
ADHD has huge knowledge gaps concerning its etiology. MicroRNAs (miRNAs) provide promising diagnostic biomarkers of human pathophysiology and may be...
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Discerning the Prospects of miRNAs as a Multi-Target Therapeutic and Diagnostic for Alzheimer’s Disease
Although over the last few decades, numerous attempts have been made to halt Alzheimer’s disease (AD) progression and mitigate its symptoms, only a...
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Circulating MiRNAs Are Associated With Low-grade Systemic Inflammation and Leptin Levels in Older Adults
Inflammaging refers to the low-grade systemic inflammation that occurs with aging present in chronic non-communicable diseases. MicroRNAs (miRNAs)...