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  1. Communication in miRNAs Between Inflammation and Cancer

    Inflammatory and immune responses are controlled by microRNAs (miRNAs), and cancer is also regulated by miRNAs. Computing analysis and evidence from...
    Yoichi Robertus Fujii in The MicroRNA 2000 Transformer
    Chapter 2023
  2. Diagnostic, Prognostic and Theranostic Potential of miRNAs in Prostate Cancer

    A novel class of gene regulators, small noncoding RNAs or microRNAs (miRNAs) has an important role in various malignancies, including prostate cancer...
    Ana Savic-Radojevic, Marija Pljesa-Ercegovac in Prostate Cancer
    Chapter 2024
  3. Deep Learning of miRNAs for Therapeutic Applications

    The RNA Precious Medical Initiative requires a safe, affordable, and sustainable device as an administration tool. Why do microRNA (miRNA) quantum...
    Yoichi Robertus Fujii in The MicroRNA 2000 Transformer
    Chapter 2023
  4. miRNAs in pancreatic cancer progression and metastasis

    Small non-coding RNA or microRNA (miRNA) are critical regulators of eukaryotic cells. Dysregulation of miRNA expression and function has been linked...

    Ellie T. Y. Mok, Jessica L. Chitty, Thomas R. Cox in Clinical & Experimental Metastasis
    Article Open access 19 January 2024
  5. Understanding the multifaceted role of miRNAs in Alzheimer’s disease pathology

    Small non-coding RNAs (miRNAs) regulate gene expression by binding to mRNA and mediating its degradation or inhibiting translation. Since miRNAs can...

    Sharanjot Kaur, Harkomal Verma, ... Anil Kumar Mantha in Metabolic Brain Disease
    Article 28 July 2023
  6. HPV16-miRNAs exert oncogenic effects through enhancers in human cervical cancer

    Background

    Cervical cancer is a human papillomavirus (HPV)-related disease. HPV type 16 (HPV16), which is the predominant cause of cervical cancer,...

    Yunuan Wang, Xueying Wang, ... Qi Lu in Cancer Cell International
    Article Open access 15 May 2024
  7. CRISPR-Cas9 screens reveal common essential miRNAs in human cancer cell lines

    Background

    Genome-wide functional screening using the CRISPR-Cas9 system is a powerful tool to uncover tumor-specific and common genetic dependencies...

    Daniel J. Merk, Linda Paul, ... Ghazaleh Tabatabai in Genome Medicine
    Article Open access 17 June 2024
  8. Differential Expression of miRNAs in Amyotrophic Lateral Sclerosis Patients

    Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease that affects nerve cells in the brain and spinal cord, causing loss of...

    Bruno Costa Gomes, Nuno Peixinho, ... António Sebastião Rodrigues in Molecular Neurobiology
    Article Open access 02 August 2023
  9. Retro-miRs: novel and functional miRNAs originating from mRNA retrotransposition

    Background

    Reverse-transcribed gene copies (retrocopies) have emerged as major sources of evolutionary novelty. MicroRNAs (miRNAs) are small and...

    Rafael L. V. Mercuri, Helena B. Conceição, ... Pedro A. F. Galante in Mobile DNA
    Article Open access 08 September 2023
  10. MiRNAs as potential therapeutic targets and biomarkers for non-traumatic intracerebral hemorrhage

    Non-traumatic intracerebral hemorrhage (ICH) is the most common type of hemorrhagic stroke, most often occurring between the ages of 45 and 60....

    Ilgiz Gareev, Ozal Beylerli, Boxian Zhao in Biomarker Research
    Article Open access 02 February 2024
  11. Identification and Characterization of Evolutionary Conserved Muskmelon Non-coding miRNAs and Their Target Proteins

    MicroRNAs (miRNAs) are short, endogenously encoded small RNAs, 18–26 nucleotides in length, which can posttranscriptionally regulate gene expression...

    Abdul Ghaffar, Naqeebullah khan, ... Samiullah in Biochemical Genetics
    Article 30 May 2024
  12. From diagnosis to resistance: a symphony of miRNAs in pheochromocytoma progression and treatment response

    Pheochromocytoma (PCC) is a neuroendocrine tumor that produces and secretes catecholamine from either the adrenal medulla or extra-adrenal locations....

    Elsayed G. E. Elsakka, Ahmed Elshafei, ... Ahmed S. Doghish in Naunyn-Schmiedeberg's Archives of Pharmacology
    Article 06 October 2023
  13. miRNAs: possible regulators of toll like receptors and inflammatory tumor microenvironment in colorectal cancer

    Background

    Colorectal cancer (CRC) is ranked as the third most commonly diagnosed cancer and the third cause of cancer related deaths. CRC is greatly...

    Marwa Matboli, Nourhan Hossam, ... Sanaa Eissa in BMC Cancer
    Article Open access 10 July 2024
  14. miRNAs contributing to the repair of tendon injury

    Tendon injury is one of the most common disorders of the musculoskeletal system, with a higher likelihood of occurrence in elderly individuals and...

    Kexin Lyu, **nyue Liu, ... Sen Li in Cell and Tissue Research
    Article Open access 30 May 2023
  15. Screening and identification of specific cluster miRNAs in N2a cells infected by H7N9 virus

    This study aims to screen and identify specific cluster miRNAs of H7N9 virus-infected N2a cells and explore the possible pathogenesis of these...

    Yitong Yin, Zengzhao Qiu, ... Shisong Fang in Virus Genes
    Article 03 July 2023
  16. A Potential Immune-Related miRNAs Regulatory Network and Corresponding Diagnostic Efficacy in Schizophrenia

    Purpose

    Immune-related pathways actively participate in the progression of schizophrenia (SCZ), however, roles of immune-related miRNAs in SCZ are...

    Fang** Liao, Qingqing Zhong, ... Li Su in Neurochemical Research
    Article 27 April 2023
  17. The role of exosome derived miRNAs in inter-cell crosstalk among insulin-related organs in type 2 diabetes mellitus

    Exosomes are small extracellular vesicles secreted by almost all cell types, and carry diverse cargo including RNA, and other substances. Recent...

    Ting Lu, Ying Zheng, ... Chengfu Yuan in Journal of Physiology and Biochemistry
    Article 03 May 2024
  18. Expression Patterns of miRNAs in Egyptian Children with ADHD: Clinical Study with Correlation Analysis

    ADHD has huge knowledge gaps concerning its etiology. MicroRNAs (miRNAs) provide promising diagnostic biomarkers of human pathophysiology and may be...

    Hala M. Zeidan, Neveen Hassan Nashaat, ... Nagwa A. Meguid in Journal of Molecular Neuroscience
    Article Open access 23 April 2024
  19. Discerning the Prospects of miRNAs as a Multi-Target Therapeutic and Diagnostic for Alzheimer’s Disease

    Although over the last few decades, numerous attempts have been made to halt Alzheimer’s disease (AD) progression and mitigate its symptoms, only a...

    Devyani Bhatnagar, Shreya Ladhe, Dileep Kumar in Molecular Neurobiology
    Article 29 June 2023
  20. Circulating MiRNAs Are Associated With Low-grade Systemic Inflammation and Leptin Levels in Older Adults

    Inflammaging refers to the low-grade systemic inflammation that occurs with aging present in chronic non-communicable diseases. MicroRNAs (miRNAs)...

    Gabrielli B. Carvalho, Paula N. Brandão-Lima, ... Marcelo M. Rogero in Inflammation
    Article 19 July 2023
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