21 Result(s)
within
Zheng Wu
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessSweat permeable and ultrahigh strength 3D PVDF piezoelectric nanoyarn fabric strain sensor
Commercial wearable piezoelectric sensors possess excellent anti-interference stability due to their electronic packaging. However, this packaging renders them barely breathable and compromises human comfort. ...
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Article
Open AccessResearch on the site selection of emergency medical facilities from the perspective of country parks
Post-epidemic era, human society entered the stage of epidemic prevention and control normalized, emergency medical facilities are an important means of epidemic prevention and control, attention-needed can pr...
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Open AccessMechanically induced pyroptosis enhances cardiosphere oxidative stress resistance and metabolism for myocardial infarction therapy
Current approaches in myocardial infarction treatment are limited by low cellular oxidative stress resistance, reducing the long-term survival of therapeutic cells. Here we develop a liquid-crystal substrate w...
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Open AccessWhole genome sequencing identifies genetic variants associated with neurogenic inflammation in rosacea
Rosacea is a chronic inflammatory skin disorder with high incidence rate. Although genetic predisposition to rosacea is suggested by existing evidence, the genetic basis remains largely unknown. Here we presen...
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Open AccessSp1 induced gene TIMP1 is related to immune cell infiltration in glioblastoma
Tumor immune microenvironment exerts a profound effect on the population of infiltrating immune cells. Tissue inhibitor of matrix metalloproteinase 1 (TIMP1) is frequently overexpressed in a variety of cells, ...
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Open AccessNecrolytic migratory erythema is an important visual cutaneous clue of glucagonoma
Glucagonoma is an extremely rare neuroendocrine tumor that arises from pancreatic islet alpha cells. Although glucagonoma is usually accompanied by a variety of characteristic clinical symptoms, early diagnosi...
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Article
Open AccessSpacetime in the brain: rapid brain network reorganization in visual processing and recovery
Functional connectivity networks (FCN) are the physiological basis of brain synchronization to integrating neural activity. They are not rigid but can reorganize under pathological conditions or during mental ...
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Article
Open AccessA broadly neutralizing humanized ACE2-targeting antibody against SARS-CoV-2 variants
The successive emergences and accelerating spread of novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineages and evolved resistance to some ongoing clinical therapeutics increase the risks ...
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Article
Open AccessElectrical stimulation of the lateral cerebellar nucleus promotes neurogenesis in rats after motor cortical ischemia
Deep brain stimulation (DBS) has been tentatively explored to promote motor recovery after stroke. Stroke could transiently activate endogenous self-repair processes, including neurogenesis in the subventricul...
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Article
Open AccessGene therapy conversion of striatal astrocytes into GABAergic neurons in mouse models of Huntington’s disease
Huntington’s disease (HD) is caused by Huntingtin (Htt) gene mutation resulting in the loss of striatal GABAergic neurons and motor functional deficits. We report here an in vivo cell conversion technology to ...
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Article
Open AccessRoom-temperature pyro-catalytic hydrogen generation of 2D few-layer black phosphorene under cold-hot alternation
Many 2D few-layer materials show piezoelectric or pyroelectric effects due to the loss-of-inversion symmetry induced by broken structure, although they are not piezoelectric or pyroelectric in the bulk. In thi...
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Article
Open AccessCirculating miRNA-21-5p as a diagnostic biomarker for pancreatic cancer: evidence from comprehensive miRNA expression profiling analysis and clinical validation
Pancreatic cancer (PC) is a highly fatal disease worldwide and is often misdiagnosed in its early stages. The exploration of novel non-invasive biomarkers will definitely benefit PC patients. Recently, circula...
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Article
Open AccessKCC2 downregulation facilitates epileptic seizures
GABAA receptor-mediated inhibition depends on the maintenance of low level intracellular [Cl−] concentration, which in adult depends on neuron specific K+-Cl− cotransporter-2 (KCC2). Previous studies have shown t...
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Open AccessAbrogating ClC-3 Inhibits LPS-induced Inflammation via Blocking the TLR4/NF-κB Pathway
This study investigated the function of a chloride channel blocker, DIDS. Both in vitro and in vivo studies found that DIDS significantly inhibits lipopolysaccharide (LPS)-induced release of proin flammatory cyto...
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Article
Open AccessMUC1 gene polymorphism rs4072037 and susceptibility to gastric cancer: a meta-analysis
The association between MUC1 polymorphism rs4072037 and the risk of gastric cancer has been described in several studies. However, these studies yielded inconsistent results, especially in different pathological ...
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Correction: Corrigendum: Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer’s disease model
Nature Communications 5: Article number 4159 doi: (2014); Published 13 June 2014; Updated 12 September 2014 The original version of this Article contained a typographical error in the spelling of ‘Alzheimer’s’...
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Article
Tonic inhibition in dentate gyrus impairs long-term potentiation and memory in an Alzheimer’s disease model
Amyloid plaques and tau tangles are common pathological hallmarks for Alzheimer’s disease (AD); however, reducing Aβ production failed to relieve the symptoms of AD patients. Here we report a high GABA (γ-amin...
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Article
Galanin neurons in the medial preoptic area govern parental behaviour
Mice display robust, stereotyped behaviours towards pups: virgin males typically attack pups, whereas virgin females and sexually experienced males and females display parental care. Here we show that virgin m...
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Correction: Corrigendum: Src activation by β-adrenoreceptors is a key switch for tumour metastasis
Nature Communications 4: Article number: 1403 (2013); Published: 29 January 2013; Updated: 29 July 2013. The original version of this Article contained a typographical error in the spelling of the author Mian ...
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Src activation by β-adrenoreceptors is a key switch for tumour metastasis
Noradrenaline can modulate multiple cellular functions important for cancer progression; however, how this single extracellular signal regulates such a broad array of cellular processes is unknown. Here we ide...
