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  1. Article

    Open Access

    The incidence trends of liver cirrhosis caused by nonalcoholic steatohepatitis via the GBD study 2017

    Nonalcoholic steatohepatitis (NASH) has rapidly become the most common cause of chronic liver diseases. We aimed to explore the incidence and distribution characteristics of NASH by sex, region and sociodemogr...

    Mimi Zhai, Zhide Liu, Jianhai Long, Qingxiang Zhou, Le** Yang in Scientific Reports (2021)

  2. Article

    Open Access

    5-HT and Intraplatelet 5-HT: a potential upstream regulator of YAP in liver regeneration

    Chao He, Mimi Zhai, Bo Shu, Chaolin Deng, Li Li in Experimental & Molecular Medicine (2019)

  3. Article

    Open Access

    Serotonin and YAP/VGLL4 Balance Correlated with Progression and Poor Prognosis of Hepatocellular Carcinoma

    YAP-TEAD complex plays an important role in tumorigenesis. 5-HT is proved to upregulate YAP expression by our previous study and VGLL4 is found to compete with YAP for binding to TEAD in several of cancers. He...

    Bo Shu, Mimi Zhai, **ongying Miao, Chao He, Chaolin Deng, Yu Fang in Scientific Reports (2018)

  4. Article

    Open Access

    Circulating miRNA-21-5p as a diagnostic biomarker for pancreatic cancer: evidence from comprehensive miRNA expression profiling analysis and clinical validation

    Pancreatic cancer (PC) is a highly fatal disease worldwide and is often misdiagnosed in its early stages. The exploration of novel non-invasive biomarkers will definitely benefit PC patients. Recently, circula...

    Kai Qu, **ng Zhang, Ting Lin, Tian Liu, Zhixin Wang, Sushun Liu in Scientific Reports (2017)

  5. No Access

    Article

    Machine perfusion versus cold storage of livers: a meta-analysis

    Different organ preservation methods are key factors influencing the results of liver transplantation. In this study, the outcomes of experimental models receiving donation after cardiac death (DCD) livers pre...

    Sushun Liu, Qing Pang, **gyao Zhang, Mimi Zhai, Sinan Liu in Frontiers of Medicine (2016)

  6. No Access

    Article

    Glutathione S-transferase P1 gene rs4147581 polymorphism predicts overall survival of patients with hepatocellular carcinoma: evidence from an enlarged study

    As the most important detoxifying enzymes in liver, glutathione S-transferases (GSTs) can protect hepatocytes against carcinogens. We conducted a large cohort study to investigate the prognostic value of single n...

    Zhixin Wang, Kai Qu, Wenquan Niu, Ting Lin, **nsen Xu, Zichao Huang in Tumor Biology (2016)

  7. Article

    Correction: Corrigendum: Serotonin Deficiency Exacerbates Acetaminophen-Induced Liver Toxicity In Mice

    Acetaminophen (APAP) overdose is a major cause of acute liver failure. Peripheral 5-hydroxytryptamine (serotonin, 5-HT) is a cytoprotective neurotransmitter which is also involved in the hepatic physiological ...

    **gyao Zhang, Sidong Song, Qing Pang, Ruiyao Zhang, Lei Zhou in Scientific Reports (2015)

  8. Article

    Open Access

    Serotonin Deficiency Exacerbates Acetaminophen-Induced Liver Toxicity In Mice

    Acetaminophen (APAP) overdose is a major cause of acute liver failure. Peripheral 5-hydroxytryptamine (serotonin, 5-HT) is a cytoprotective neurotransmitter which is also involved in the hepatic physiological ...

    **gyao Zhang, Sidong Song, Qing Pang, Ruiyao Zhang, Lei Zhou in Scientific Reports (2015)