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Article
Abnormal Degraded Tapetum 1 (ADT1) is required for tapetal cell death and pollen development in rice
The timely degradation of tapetum, the innermost somatic anther cell layer in flowering plants, is critical for pollen development. Although several genes involved in tapetum development have been characterize...
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Article
Effect of Yb Addition on the Microstructure and Mechanical Properties of the Mg–4Sm–3Gd–0.5Zr Alloy
The microstructure and mechanical properties of Mg-4Sm-3Gd-xYb-0.5Zr (x = 0, 1, 2, 3 wt%) alloys under different heat treatment states were systematically investigated, as well as the influence mechanism of the Y...
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Article
Unveiling mitochondrial and ribosomal gene deregulation and tumor microenvironment dynamics in acute myeloid leukemia
Acute myeloid leukemia (AML) is a malignant clonal hematopoietic disease with a poor prognosis. Understanding the interaction between leukemic cells and the tumor microenvironment (TME) can help predict the pr...
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Article
Functional characterization of OsCAT2 gene in rice that regulates ROS scavenging and plant growth and development
Catalase (CAT) is an essential antioxida existing within nearly every living organism. The present work aimed to identify and functionally characterize OsCAT2 in rice. Expression analysis revealed that OsCAT2 mai...
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Article
Open AccessSweat permeable and ultrahigh strength 3D PVDF piezoelectric nanoyarn fabric strain sensor
Commercial wearable piezoelectric sensors possess excellent anti-interference stability due to their electronic packaging. However, this packaging renders them barely breathable and compromises human comfort. ...
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Article
Open AccessEfficacy and safety of tislelizumab plus lenvatinib as first-line treatment in patients with unresectable hepatocellular carcinoma: a multicenter, single-arm, phase 2 trial
Lenvatinib is widely used in treatment of unresectable hepatocellular carcinoma (uHCC), but the benefit of its combination with immunotherapy needs to be verified. This study evaluated the efficacy and safety ...
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Article
Comprehensive pan-cancer analysis reveals prognostic implications of TMEM92 in the tumor immune microenvironment
Transmembrane protein 92 (TMEM92) has been implicated in the facilitation of tumor progression. Nevertheless, comprehensive analyses concerning the prognostic significance of TMEM92, as well as its role in imm...
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Article
Open AccessPlatinum-based adjuvant chemoradiotherapy versus adjuvant radiotherapy in patients with head and neck adenoid cystic carcinoma
The objective of the study was to assess the effectiveness and toxicity of platinum-based adjuvant chemoradiotherapy (POCRT) in comparison to postoperative radiotherapy (PORT) in patients with head and neck ad...
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Article
Open AccessBlocking CIRP protects against acute pancreatitis by improving mitochondrial function and suppressing pyroptosis in acinar cells
Acute pancreatitis (AP) continues to pose a major challenge as targeted therapeutic interventions are absent. Mitochondrial dysfunction and inflammasome-dependent pyroptosis are involved in the pathogenic mech...
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Article
Machine learning–based coronary artery calcium score predicted from clinical variables as a prognostic indicator in patients referred for invasive coronary angiography
Utilising readily available clinical variables, we aimed to develop and validate a novel machine learning (ML) model to predict severe coronary calcification, and further assessed its prognostic significance.
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Article
Omission of radiotherapy to lymph node level III in patients with cN0 adenoid cystic carcinoma of the major salivary gland: a single center experience
Due to the rarity of adenoid cystic carcinoma (ACC) of the major salivary gland, there is no consensus on the extent of prophylactic neck irradiation (PNI) for patients with clinically negative lymph nodes (cN...
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Chapter and Conference Paper
Output Consensus of Heterogeneous Discrete-Time Multi-agent Systems over Switching Digraphs
The focus of this paper is the investigation of output consensus problems in heterogeneous discrete-time linear multi-agent systems with switching digraphs. The modified algebra Riccati inequality and a topolo...
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Article
Open AccessNotch3 restricts metastasis of breast cancers through regulation of the JAK/STAT5A signaling pathway
To explore the potential role of signal transducer and activator of transcription 5A (STAT5A) in the metastasis of breast cancer, and its mechanism of regulation underlying.
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Article
Using green background for dermatological images to improve deep learning-based image classification
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Article
Open AccessClinical Outcome of Paclitaxel-Coated Balloon Angioplasty Versus Drug-Eluting Stent Implantation for the Treatment of Coronary Drug-Eluting Stent In-Stent Chronic Total Occlusion
In-stent chronic total occlusion (IS-CTO) represents a unique challenge for percutaneous coronary intervention. Whether the optimal treatment for IS-CTO is angioplasty with paclitaxel-coated balloons (PCBs) or...
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Article
Open AccessResearch on the site selection of emergency medical facilities from the perspective of country parks
Post-epidemic era, human society entered the stage of epidemic prevention and control normalized, emergency medical facilities are an important means of epidemic prevention and control, attention-needed can pr...
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Article
Open AccessMechanically induced pyroptosis enhances cardiosphere oxidative stress resistance and metabolism for myocardial infarction therapy
Current approaches in myocardial infarction treatment are limited by low cellular oxidative stress resistance, reducing the long-term survival of therapeutic cells. Here we develop a liquid-crystal substrate w...
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Article
Aβ Induces Neuroinflammation and Microglial M1 Polarization via cGAS-STING-IFITM3 Signaling Pathway in BV-2 Cells
Microglia, innate immune cells of the brain, constantly monitor the dynamic changes of the brain microenvironment under physiological conditions and respond in time. Growing evidence suggests that microglia-me...
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Article
Open AccessWhole genome sequencing identifies genetic variants associated with neurogenic inflammation in rosacea
Rosacea is a chronic inflammatory skin disorder with high incidence rate. Although genetic predisposition to rosacea is suggested by existing evidence, the genetic basis remains largely unknown. Here we presen...
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Article
Solar thermal swing adsorption on porous carbon monoliths for high-performance CO2 capture
Utilizing solar energy for sorbent regeneration during the CO2 swing adsorption process could potentially reduce CO2 capture costs. This study describes a new technique—solar thermal swing adsorption (STSA) for C...
