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  1. No Access

    Article

    A new mouse limb mutation identifies a Twist allele that requires interacting loci on Chromosome 4 for its phenotypic expression

    Pluridigite (Pdt) is a semi-dominant mutation obtained after a mutagenesis experiment with ethyl-nitroso-urea (ENU). The mutant exhibits abnormal skeletal pattern formation characterized by the formation of extra...

    Isabelle Blanc, Antoine Bach, Yvan Lallemand, Fabienne Perrin-Schmitt… in Mammalian Genome (2003)

  2. No Access

    Article

    Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase

    A transgenic mouse strain with early and uniform expres sion of the Cre site-specific recombinase is described. In this strain, PGK-Crem, Cre is driven by the early acting PGK-1 promoter, but, probably due to ...

    Yvan Lallemand, Victor Luria, Rebecca Haffner-Krausz, Peter Lonai in Transgenic Research (1998)

  3. No Access

    Article

    Epilepsy and brain abnormalities in mice lacking the Otx1 gene

    The morphogenesis of the brain and the differentiation of the neural structures are highly complex processes. A series of temporally and spatially regulated morphogenetic events gives rise to smaller areas tha...

    Dario Acampora, Sylvie Mazan, Virginia Avantaggiato, Paolo Barone… in Nature Genetics (1996)

  4. No Access

    Article

    Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain

    NICOTINE affects many aspects of behaviour including learning and memory1,2 through its interaction with neuronal nicotinic acetylcholine receptors (nAChR). Functional nAChRs are pentameric proteins containing at...

    Marina R. Picciotto, Michele Zoli, Clement Léna, Alain Bessis, Yvan Lallemand… in Nature (1995)