7 Result(s)
within
Rebecca Haffner-Krausz
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Protocol
Tackling Tissue Macrophage Heterogeneity by SplitCre Transgenesis
Macrophages represent a broad spectrum of distinct, but closely related tissue-resident immune cells. This presents a major challenge for the study of functional aspects of these cells using classical Cre reco...
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Article
Cognate microglia–T cell interactions shape the functional regulatory T cell pool in experimental autoimmune encephalomyelitis pathology
Microglia, the parenchymal brain macrophages of the central nervous system, have emerged as critical players in brain development and homeostasis. The immune functions of these cells, however, remain less well...
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Article
TT2019 meeting report on the 15th Transgenic Technology Meeting in Kobe, Japan
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Article
Open AccessDevelopmental activities of the complement pathway in migrating neurons
In recent years the notion that malfunctioning of the immune system may result in developmental brain diseases has emerged. However, the role of immune molecules in the develo** brain has not been well explo...
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Article
Open AccessFunctional Phenoty** of the Maternal Albumin Turnover in the Mouse Placenta by Dynamic Contrast-Enhanced MRI
The purpose of this study was to develop a tool for functional phenoty** of the maternal circulation in the mouse placenta.
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Article
CKIα ablation highlights a critical role for p53 in invasiveness control
In a mouse model of intestinal cancer, Yinon Ben-Neriah and colleagues show that in the absence of CK1-α, the loss of p53 dramatically enhances tumour progression and metastasis. The tumour repressor p53 norma...
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Article
Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site-specific recombinase
A transgenic mouse strain with early and uniform expres sion of the Cre site-specific recombinase is described. In this strain, PGK-Crem, Cre is driven by the early acting PGK-1 promoter, but, probably due to ...
