141 Result(s)

Article

Risk of diabetes mellitus based on the interactive association between G6PD rs72554664 polymorphism and sex in Taiwan Biobank individuals

The presence of glucose-6-phosphate dehydrogenase (G6PD) deficiency may increase the risk of type 2 diabetes mellitus (T2DM), with differing prevalence between males and females. Although G6PD deficiency is an X-...

Yen-Lin Chang, Oswald Ndi Nfor, Ying-Hsiang Chou, Chih-Hsuan Hsiao… in Scientific Reports (2024)

Article

Prodrug-conjugated tumor-seeking commensals for targeted cancer therapy

Prodrugs have been explored as an alternative to conventional chemotherapy; however, their target specificity remains limited. The tumor microenvironment harbors a range of microorganisms that potentially serv...

Haosheng Shen, Changyu Zhang, Shengjie Li, Yuanmei Liang… in Nature Communications (2024)

Article

Predicting early mortality and severe intraventricular hemorrhage in very-low birth weight preterm infants: a nationwide, multicenter study using machine learning

Our aim was to develop a machine learning-based predictor for early mortality and severe intraventricular hemorrhage (IVH) in very-low birth weight (VLBW) preterm infants in Taiwan. We collected retrospective ...

Yun-Hsiang Yang, Ts-Ting Wang, Yi-Han Su, Wei-Ying Chu, Wei-Ting Lin… in Scientific Reports (2024)

Article

Proteomic analysis of serum extracellular vesicles from biliary tract infection patients to identify novel biomarkers

Biliary tract infection (BTI), a commonly occurring abdominal disease, despite being extensively studied for its initiation and underlying mechanisms, continues to pose a challenge in the quest for identifying...

Chih-Jung Chang, Yung-Ning Huang, Yang-Bor Lu, Yi Zhang, **-Hua Wu… in Scientific Reports (2024)

Article

Alkali metal bilayer intercalation in graphene

Alkali metal (AM) intercalation between graphene layers holds promise for electronic manipulation and energy storage, yet the underlying mechanism remains challenging to fully comprehend despite extensive rese...

Yung-Chang Lin, Rika Matsumoto, Qiunan Liu, Pablo Solís-Fernández… in Nature Communications (2024)

Article

Dual-plasmonic Au@Cu₇S₄ yolk@shell nanocrystals for photocatalytic hydrogen production across visible to near infrared spectral region

Near infrared energy remains untapped toward the maneuvering of entire solar spectrum harvesting for fulfilling the nuts and bolts of solar hydrogen production. We report the use of Au@Cu₇S₄ yolk@shell nanocrysta...

Chun-Wen Tsao, Sudhakar Narra, Jui-Cheng Kao, Yu-Chang Lin… in Nature Communications (2024)

Article

Enhanced antioxidant, tyrosinase inhibition, and anti-inflammatory activities of Praeparatum mungo and three of its derivatives

The main objective of this study is to explore the functions of Praeparatum mungo (PM) and three of its derivatives, Praeparatum mungo/turmeric (PM/T), Praeparatum mungo/bromelain (PM/B), and Praeparatum mungo/in...

Tzu-Chin Chang, Jie-Ling Cao, Yung-Sheng Lin, Shu-Ling Huang in Scientific Reports (2023)

Article

Thermal indices for human biometeorology based on Python

Thermal indices, such as Predicted Mean Vote, Outdoor Standard Effective Temperature, Physiologically Equivalent Temperature, and Universal Thermal Climate Index, are essential for the evaluation of thermal pe...

Yung-Chang Chen in Scientific Reports (2023)

Article

Clinical outcomes between elderly ESKD patients under peritoneal dialysis and hemodialysis: a national cohort study

With ageing populations, new elderly end-stage kidney disease (ESKD) cases rise. Unlike younger patients, elderly ESKD patients are less likely to undergo kidney transplant, and therefore the decision of recei...

Yu-Kai Peng, Tzong-Shyuan Tai, Chao-Yi Wu, Chung-Ying Tsai… in Scientific Reports (2023)

Article

A comparative analysis of aerosol exposure and prevention strategies in bystander, pre-hospital, and inpatient cardiopulmonary resuscitation using simulation manikins

To evaluate aerosol exposure risk and prevention strategies during bystander, pre-hospital, and inpatient cardiopulmonary resuscitation (CPR). This study compared hands-only CPR, CPR with a surgical or N95 mas...

Tzu-Yao Hung, Chung-Shiung Wen, Sheng-Han Yu, Yi-Chang Chen… in Scientific Reports (2023)

Article

Transparent tissue in solid state for solvent-free and antifade 3D imaging

Optical clearing with high-refractive-index (high-n) reagents is essential for 3D tissue imaging. However, the current liquid-based clearing condition and dye environment suffer from solvent evaporation and photo...

Fu-Ting Hsiao, Hung-Jen Chien, Ya-Hsien Chou, Shih-Jung Peng… in Nature Communications (2023)

Article

Methionine consumption by cancer cells drives a progressive upregulation of PD-1 expression in CD4 T cells

Programmed cell death protein 1 (PD-1), expressed on tumor-infiltrating T cells, is a T cell exhaustion marker. The mechanisms underlying PD-1 upregulation in CD4 T cells remain unknown. Here we develop nutrie...

Mahesh Pandit, Yun-Seo Kil, Jae-Hee Ahn, Ram Hari Pokhrel, Ye Gu… in Nature Communications (2023)

Article

N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry

Oxidized cysteine residues are highly reactive and can form functional covalent conjugates, of which the allosteric redox switch formed by the lysine-cysteine NOS bridge is an example. Here, we report a noncan...

Yung-Lin Wang, Chin-Yuan Chang, Ning-Shian Hsu, I-Wen Lo… in Nature Communications (2023)

Article

Endogenous retroviruses and TDP-43 proteinopathy form a sustaining feedback driving intercellular spread of Drosophila neurodegeneration

Inter-cellular movement of “prion-like” proteins is thought to explain propagation of neurodegeneration between cells. For example, propagation of abnormally phosphorylated cytoplasmic inclusions of TAR-DNA-Bi...

Yung-Heng Chang, Josh Dubnau in Nature Communications (2023)

Article

The scaled-invariant Planckian metal and quantum criticality in Ce_1−xNd_xCoIn₅

The mysterious Planckian metal state, showing perfect T-linear resistivity associated with universal scattering rate, 1/τ = αk_BT/ℏ with α ~ 1, has been observed in the normal state of various strongly correlated ...

Yung-Yeh Chang, Hechang Lei, C. Petrovic, Chung-Hou Chung in Nature Communications (2023)

Article

Allele-specific polymerase chain reaction can determine the diplotype of NUDT15 variants in patients with childhood acute lymphoblastic Leukemia

Mercaptopurine intolerance is an adverse effect of mercaptopurine administration in pediatric patients with acute lymphoblastic leukemia (ALL). NUDT15 variants have emerged as major determinants of mercaptopurine...

Chih-Hsiang Yu, Ya-Hsuan Chang, Der-Shiun Wang, Shiann-Tarng Jou… in Scientific Reports (2023)

Article

A feasibility study of wireless inductively coupled surface coil for MR-guided high-intensity focused ultrasound ablation of rodents on clinical MRI systems

Recently, to conduct preclinical imaging research on clinical MRI systems has become an attractive alternative to researchers due to its wide availability, cost, and translational application to clinical human...

Chien-Feng Judith Huang, Win-Li Lin, San-Chao Hwang, Ching Yao… in Scientific Reports (2022)

Article

Author Correction: Heterodimensional superlattice with in-plane anomalous Hall effect

Jiadong Zhou, Wenjie Zhang, Yung-Chang Lin, ** Cao, Yao Zhou, Wei Jiang… in Nature (2022)

Article

Aminoglycosides use has a risk of acute kidney injury in patients without prior chronic kidney disease

The outcome of acute kidney injury (AKI) as a result of aminoglycosides (AGs) use remains uncertain in patients without prior chronic kidney disease (CKD). Therefore, we explored the outcomes of AGs use on AKI...

Chu-Lin Chou, Nai-Chen Chuang, Hui-Wen Chiu, Chia-Te Liao… in Scientific Reports (2022)

Article

Death anxiety as mediator of relationship between renunciation of desire and mental health as predicted by Nonself Theory

In the present paper, we report two studies examining the relationships among renunciation of desires, death anxiety, and mental health. In the first study, we constructed the Desire Questionnaire (DQ), which ...

Yi-Fen Kuo, Yun-Ming Chang, Mei-Fang Lin, Ming-Lung Wu… in Scientific Reports (2022)