220 Result(s)
within
Yong-** Yoon
Life Sciences
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Article
Genome-based taxonomic identification and safety assessment of an Enterococcus strain isolated from a homemade dairy product
The aim of this study was to explore the taxonomic identification and evaluate the safety of a bacterium, Enterococcus lactis IDCC 2105, isolated from homemade cheese in Korea, using whole genome sequence (WGS) a...
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BdASR5 Positively Regulates Drought Tolerance by Mediating ABA Signaling Pathway in Brachypodium distachyon
Abscisic acid-, stress-, and ripening-induced (ASR) proteins are involved in response to abiotic stresses. However, the precise role of Brachypodium ASR genes in enhancing tolerance under drought stress condition...
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Open AccessAkt enhances the vulnerability of cancer cells to VCP/p97 inhibition-mediated paraptosis
Valosin-containing protein (VCP)/p97, an AAA+ ATPase critical for maintaining proteostasis, emerges as a promising target for cancer therapy. This study reveals that targeting VCP selectively eliminates breast...
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Emticicia fluvialis sp. nov., a potential hormone-degrading bacterium isolated from Nakdong River, Republic of Korea
A novel species of the genus Emticicia, designated BHSR1T, was isolated from a water sample that was collected from the Nakdong River, Republic of Korea, and its taxonomic affiliation was studied using a polyphas...
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Open AccessADSC secretome constrains NK cell activity by attenuating IL-2-mediated JAK-STAT and AKT signaling pathway via upregulation of CIS and DUSP4
Mesenchymal stem cells (MSCs) have immunomodulatory properties and therapeutic effects on autoimmune diseases through their secreted factors, referred to as the secretome. However, the specific key factors of ...
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Characterization of chemoresistant human non-small cell lung cancer cells by metabolic and lipidomic profiling
Lung cancer is one of the most malignant cancers and the leading cause of cancer-related deaths worldwide, while acquired chemoresistance would represent a major problem in the treatment of non-small cell lung...
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Development of the genoty** marker for Reeves’ turtle (Mauremys reevesii) using high-resolution melting (HRM) analysis
The Reeves’ turtle, Mauremys reevesii, resides in freshwater bodies of Korea, China, Japan, and Taiwan, and is designated as an endangered species in the Republic of Korea (ROK). However, international pet trade ...
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Open AccessGenome-wide association study of resistance to anthracnose in pepper (Capsicum chinense) germplasm
Anthracnose is a fungal disease caused by Colletotrichum spp. that has a significant impact on worldwide pepper production. Colletotrichum scovillei is the most common pathogenic anthracnose-causing species in th...
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The Effects of Cordycepin on Benign Prostatic Hyperplasia through Autophagy Activation in BPH-1 Cell Line
Benign prostatic hyperplasia (BPH) is an age-related disease and characterized by nonmalignant enlargement of the prostate gland. Currently, it’s etiology remains unclear. A previous report showed that autopha...
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Breast Tissue Reconstruction Using Polycaprolactone Ball Scaffolds in a Partial Mastectomy Pig Model
Breast cancer patients suffer from lowered quality of life (QoL) after surgery. Breast conservancy surgery (BCS) such as partial mastectomy is being practiced and studied as an alternative to solve this proble...
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Integrative analysis of risk factors for immune-related adverse events of checkpoint blockade therapy in cancer
Immune-related adverse events (irAEs) induced by checkpoint inhibitors involve a multitude of different risk factors. Here, to interrogate the multifaceted underlying mechanisms, we compiled germline exomes an...
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A rice seed-specific glycine-rich protein OsDOR1 interacts with GID1 to repress GA signaling and regulates seed dormancy
Seed dormancy is an important agronomic trait under the control of complex genetic and environmental interactions, which have not been yet comprehensively understood. From the field screening of rice mutant li...
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Gene expression related to lung cancer altered by PHMG-p treatment in PBTE cells
Humidifier disinfectants (HDs), including polyhexamethylene guanidine phosphate (PHMG-p), are commonly used in Korea to prevent microbial growth. Epidemiological studies show that PHMG-p causes severe lung inj...
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Evaluating the comparative MT1B, MT1F, MT1G, and MT1H expression in human pulmonary alveolar epithelial cells treated with polyhexamethylene guanidine-phosphate, chloromethylisothiazolinone/methylisothiazolinone, oligo(2-(2-ethoxy)ethoxyethyl guanidinium chloride, benzalkonium chloride, and sodium dichloroisocyanurate
We previously reported the increase in expression of metallothionein1 (MT1) B, MT1F, MT1G, and MT1H after exposure to polyhexamethylene guanidine phosphate (PHMG-p), a humidifier disinfectant, in human pulmona...
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3-Hydroxymorphinan protects against hypoxia-induced cell death in primary astrocyte by regulating Ca2+ influx and the glutamate homeostasis
Hypoxia is a pathological phenomenon of the central nervous system that occurs during ischemia and stroke, leading to brain cell damage. Astrocytes play an important role in maintaining homeostasis in the brai...
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Open AccessPopulation genetic structure and conservation management of hill pigeons (Columba rupestris) recently endangered in South Korea
Hill pigeons (Columba rupestris) are close to local extinction (ca. less than 100 individuals) in South Korea where a variety of conservation management procedures are urgently required.
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Integrated analysis of miRNA and mRNA expression profiles in diabetic mouse kidney treated to Korean Red Ginseng
Diabetes mellitus (DM) and its complications, including diabetic nephropathy, are rapidly increasing public health concerns. Korean Red Ginseng (KRG) is a popular herbal medicine that has many biological effec...
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Open AccessA mannose-sensing AraC-type transcriptional activator regulates cell–cell aggregation of Vibrio cholerae
In addition to catalyzing coupled transport and phosphorylation of carbohydrates, the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS) regulates various physiological processes in most bacteria...
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Targeted erasure of DNA methylation by TET3 drives adipogenic reprogramming and differentiation
DNA methylation is a crucial epigenetic modification in the establishment of cell-type-specific characteristics. However, how DNA methylation is selectively reprogrammed at adipocyte-specific loci during adipo...
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Open AccessLaboratory information management system for COVID-19 non-clinical efficacy trial data
As the number of large-scale studies involving multiple organizations producing data has steadily increased, an integrated system for a common interoperable format is needed. In response to the coronavirus dis...
