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Article
3-Hydroxymorphinan protects against hypoxia-induced cell death in primary astrocyte by regulating Ca2+ influx and the glutamate homeostasis
Hypoxia is a pathological phenomenon of the central nervous system that occurs during ischemia and stroke, leading to brain cell damage. Astrocytes play an important role in maintaining homeostasis in the brai...
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Article
Effect of sodium butyrate on the assembly, charge variants, and galactosylation of antibody produced in recombinant Chinese hamster ovary cells
Sodium butyrate (NaBu) is known to increase the specific productivity of recombinant Chinese hamster ovary (rCHO) cells. To understand the effects of NaBu on the product quality, rCHO cells producing monoclona...
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Article
A real-time PCR-based amelogenin Y allele dropout assessment model in gender ty** of degraded DNA samples
Allelic dropout due to stochastic variation in degraded small quantity DNA appears to be one of the most serious genoty** errors. Most methods require PCR replication to address this problem. The small amoun...
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Article
Immunohistochemical study on the distribution of neuronal nitric oxide synthase-immunoreactive neurons in the spinal cord of aged rat
Despite in vivo studies suggesting an important function for nitric oxide (NO) in the spinal cord in the transmission of pain signals, sympathetic nerve activity and presumably other spinal functions, changes of ...
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Article
Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II
Platelet-derived growth factor (PDGF) is a potent mitogenic and migratory factor that regulates the tyrosine phosphorylation of a variety of signalling proteins via intracellular production of H2O2 (refs 1, 2–3)....
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Article
Open Accessβ PAK-interacting exchange factor may regulate actin cytoskeleton through interaction with actin
p21-activated kinase (PAK)-interacting exchange factor (PIX) is known to be involved in regulation of Cdc42/Rac GTPases and PAK activity. PIX binds to the proline-rich region of PAK, and regulates biological e...
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Article
Inhibition of SIN-1–Induced Change in Mitochondrial Membrane Permeability in PC12 Cells by Dopamine
Dopamine (50 or 100 μM) attenuated the nuclear damage and cell death due to 500 μM SIN-1, a donor of superoxide and nitric oxide, in differentiated PC12 cells whereas 200 μM dopamine did not depress cell death...
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Article
P53 mediates ceramide-induced apoptosis in SKN-SH cells
Ceramide induces apoptotic cell death in a dose- and time-dependent manner in neuroblastoma SKN-SH cells. Pretreatment with caspase inhibitors blocks cell death, suggesting that a set of caspase activities inc...
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Article
Open AccessProduction and characterization of monoclonal antibodies against amphiphysins
Amphiphysin I and II, proteins enriched in nerve terminals, form heterodimers and interact with dynamin and synaptojanin through their Src homology 3 (SH3) domain. In order to study the expression profile of A...
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Article
Effects of Nd2O3 on the microwave dielectric properties of BiNbO4 ceramics
Effects of Nd substitution with Bi on the microwave dielectric properties of BiNbO4 were studied. Bi1−xNdxNbO4 ceramics sintered at 920–980 °C consisted of orthorhombic and triclinic phases. The amount of triclin...
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Article
Characteristics of tapped microstrip bandpass filter in BiNbO4 ceramics
The dielectric properties of BiNbO4 (BN ceramics) sintered at low temperature with CuO and V2O5 additives were determined. BN ceramics containing 0.07 wt% V2O5 and 0.03–0.05 wt% CuO sintered at 900 °C had a di...
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Article
Dispersion characteristics of the complex permeability-permittivity of Ni-Zn ferrite-epoxy composites
The effects of volume fraction and particle size of ferrite on the electric and magnetic properties of epoxy composites containing Ni-Zn ferrite were investigated. The composites were prepared by the cement mi...
